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Home » Topics » Drugs » Monoclonal antibody

Monoclonal antibody
Monoclonal antibody RSS Feed RSS

Handshake with digital globe overlay

Abion strikes $1.3B antibody drug deal with unidentified partner

July 1, 2025
By Marian (YoonJee) Chu
No Comments
Abion Inc. signed a potential $1.315 billion deal with an anonymous partner June 22, granting the counterparty exclusive global rights to a preclinical claudin 3-targeting monoclonal antibody, ABN-501, and the potential to license four more protein targeting antibodies.
Read More
Tree in the shape of human head losing leaves
Neurology/psychiatric

Encoding an entire mAb against TDP-43 into AAV to treat neurodegenerative diseases

June 30, 2025
No Comments
Monoclonal antibodies show strong therapeutic potential against neurodegenerative diseases, but a major challenge is ensuring that they can arrive unharmed in the brain at sufficient concentrations. One way around this challenge is to vectorize the monoclonal antibody: encode it within a vector that can infect target cells in the brain and express the antibody in situ.
Read More
Handshake with digital globe overlay

Abion strikes $1.3B antibody drug deal with unidentified partner

June 27, 2025
By Marian (YoonJee) Chu
No Comments
Abion Inc. signed a potential $1.315 billion deal with an anonymous partner June 22, granting the counterparty exclusive global rights to a preclinical claudin 3-targeting monoclonal antibody, ABN-501, and the potential to license four more protein targeting antibodies.
Read More
Art concept for monoclonal antibodies
Hematologic

Hemab presents data for HMB-002 in von Willebrand disease

June 27, 2025
No Comments
Hemab ApS recently presented preclinical data on its human monoclonal antibody against von Willebrand factor (vWF), HMB-002, for the treatment of von Willebrand disease.
Read More
Enflonsia

ACIP delivers good news for Merck, makes unprecedented precedent

June 26, 2025
By Mari Serebrov
No Comments
Despite the controversies swirling around the June meeting of the U.S. CDC’s Advisory Committee for Immunization Practices (ACIP), the reconstituted committee delivered good news to Merck & Co. Inc. when it voted 5-2 June 26 to recommend that infants younger than 8 months who are not protected by maternal vaccination get one dose of a monoclonal as they head into their first respiratory syncytial virus season.
Read More
Handshake with digital globe overlay

Abion strikes $1.3B antibody drug deal with unidentified partner

June 26, 2025
By Marian (YoonJee) Chu
No Comments
Abion Inc. signed a potential $1.315 billion deal with an anonymous partner June 22, granting the counterparty exclusive global rights to a preclinical claudin 3-targeting monoclonal antibody, ABN-501, and the potential to license four more protein targeting antibodies.
Read More

Keymed launching Stapokibart, advancing pipeline, with $125M raise

June 24, 2025
By Tamra Sami
No Comments
Keymed Biosciences Co. Ltd. has raised HK$982 million (US$125 million) in a placement on the Hong Kong Stock Exchange (HKEX:2162) to commercialize its IL-4Rα monoclonal antibody CM-310 branded as Stapokibart, and to advance its larger pipeline.
Read More

Keymed launching Stapokibart, advancing pipeline, with $125M raise

June 20, 2025
By Tamra Sami
No Comments
Keymed Biosciences Co. Ltd. has raised HK$982 million (US$125 million) in a placement on the Hong Kong Stock Exchange (HKEX:2162) to commercialize its IL-4Rα monoclonal antibody CM-310 branded as Stapokibart, and to advance its larger pipeline.
Read More
Andembry

New orphan drug, CSL’s garadacimab, cleared for hereditary angioedema

June 17, 2025
By Karen Carey and Tamra Sami
No Comments
Following a complete response letter issued last October over CMC issues, CSL Behring LLC gained U.S. FDA approval June 16 of its humanized anti-factor XIIa monoclonal antibody, garadacimab (CSL-312), to prevent hereditary angioedema attacks.
Read More
Colorized micrograph of breast cancer cells with the HER2 protein (red).
Immuno-oncology

Characterization of new first-in-class tumor-specific anti-HER2 antibody

June 16, 2025
No Comments
Researchers at the Olivia Newton-John Cancer Research Institute and collaborators have developed a new anti-HER2 monoclonal antibody, mAb104, which targets a conformationally exposed, tumor-specific epitope in domain II of the HER2 protein.
Read More
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