With a potential COVID-19 vaccine moving closer to reality and the U.S government signing contracts for millions of potential doses, an unresolved question is who should be at the front of the line to get those first doses.

DUBLIN – Sanofi SA and Regeneron Pharmaceuticals Inc. are terminating all further development in COVID-19 of their interleukin-6 receptor inhibitor, Kevzara, following the antibody’s failure to meet the primary endpoint, as well as a key survival endpoint.

Regulatory snapshots, including global drug submissions and approvals, clinical trial approvals and other regulatory decisions and designations: Arch, Astrazeneca, Athenex, BMS, GSK, Inmune, Mirum, Nkmax, Novo, Plus, Vertex.

Biopharma happenings, including deals and partnerships, grants, preclinical data and other news in brief: Aegis, Altimmune, Altum, Antios, Applied Biomath, Aptorum, Astellas, Astrazeneca, Bavarian Nordic, Betterlife, Boston Pharmaceuticals, Daré, Dcprime, Domain, Elix, Elixirgen, Emergex, Entos, Flame, Glaxosmithkline, HDT Bio, Humanigen, Immpronano, Immunobrain, Medicinova, Mirum, Neuclone, Northwest Biotherapeutics, Novartis, Oxford Biomedica, PCI, Pfizer, Recce, Relation Therapeutics, Revision, Rodeo, Sonnet, Tavanta.

Clinical updates, including trial initiations, enrollment status and data readouts and publications: Alimera, Annovis, Aptevo, Arena, Astrazeneca, Biophytis, BMS, Cartesian, Clear Creek, Genfit, Hepion, Immunomic, Innovent, Iveric, Kuros, Orchard, Oxurion, Sanofi, Transcenta.

Biopharma happenings, including deals and partnerships, grants, preclinical data and other news in brief: Agex, Arrakis, Bharat, Biocryst, Cheplapharm, Elektrofi, Glycomimetics, Immutep, Kalos, Leo, Ligand, Lineage, Maat, Metagenomi, Mindset, Novavax, PDL, Qualigen, Resverlogix, Regulus, Sanofi, Seneca, Sotio, Unum, Vallaurix, Vor.

Clinical updates, including trial initiations, enrollment status and data readouts and publications: Acasti, Akari, Axsome, Bluebird, Eiger, Embera, GSK, Imbrium, Kiadis, Maat, Mirum, NGM, Novan, Novartis, Orpheris, Provention, Regenerx, Shattuck, VBI, Vir.

The latest global regulatory news, changes and updates affecting biopharma.

Regulatory snapshots, including global drug submissions and approvals, clinical trial approvals and other regulatory decisions and designations: Biocryst, Can-Fite, Cormedix, Cstone, FDS, Gilead, Lipocine, Mustang, Omeros, Oncopeptides, Revive, Sound, Spero, Velosbio, Xortx.