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Home » Authors » Nuala Moran

Articles by Nuala Moran

Year in review 2024 - Europe funding

European VC improves in 2024, driven by ADCs and CNS, inflammatory drugs

Dec. 27, 2024
By Nuala Moran
After the funding feast sparked by the pandemic, European biotech has emerged from the famine that followed, with venture capital raised this year finally exceeding the 2020 total.After the funding feast sparked by the pandemic, European biotech has emerged from the famine that followed, with venture capital raised this year finally exceeding the 2020 total.
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CRL for Zealand Pharma's glepaglutide; Novo’s Cagrisema disappoints

Dec. 20, 2024
By Nuala Moran
Shares in Zealand Pharma A/S (CO:ZEAL) dropped 22.4% to as low as DKK587 (US$82.16) on Dec. 20, after the U.S. FDA issued a complete response letter (CRL) for glepaglutide in the treatment of short bowel syndrome.
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Hand holding gear, dollar sign

Ottimo’s $140M series A to advance PD-1/VEGF inhibitor

Dec. 19, 2024
By Nuala Moran
Ottimo Pharma Ltd. is equipped to file an IND and take its lead bifunctional antibody into phase II development, after closing a $140 million series A. The round will accelerate development of jankistomig, which targets the PD-1 immune checkpoint whilst inhibiting tumor angiogenesis by neutralizing vascular endothelial growth factor (VEGF).
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Ozempic pen and packaging

Danish regulators question possible Ozempic link to rare eye condition

Dec. 17, 2024
By Nuala Moran
The Danish Medicines Agency is to ask the EMA’s pharmacovigilance committee to investigate a potential increased risk of an acute eye condition in diabetic patients being treated with the glucagon-like peptide-1 receptor agonist Ozempic (semaglutide).
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Puretech’s modified pirfenidone impresses in phase IIb IPF trial

Dec. 16, 2024
By Nuala Moran
Puretech Health plc has announced phase IIb data showing its reformulation of pirfenidone has improved the tolerability and increased the efficacy of the marketed antifibrotic in the treatment of idiopathic pulmonary fibrosis. The tweak on the original molecule involved substituting three hydrogen atoms with three of the heavier counterpart, deuterium, improving stability, whilst retaining the antifibrotic effect.
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Welireg, Emcitate among drugs EMA recommends for approval

Dec. 13, 2024
By Nuala Moran
The EMA’s Committee for Medicinal Products for Human Use recommended 17 drugs for approval at its December meeting, bringing the total for 2024 to 114. That is up from the 77 drugs recommended for approval in 2023, of which 39 were novel.
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Concept of business partnership

Relation inks two GSK deals tackling osteoarthritis, fibrotic disease

Dec. 12, 2024
By Nuala Moran
Relation Therapeutics Ltd. has delivered the first commercial validation of its combined wet lab/in silico platform for homing in on disease-related genes in the thick of the genome, signing two collaboration agreements with GSK plc, with a potential value of $200 million per target.
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Noema adds new investor as it nears phase II readouts

Dec. 11, 2024
By Nuala Moran
CNS specialist Noema Pharma AG has added a further $44 million to its series B, bringing the total for the round to $147 million. The new financing bolsters the balance sheet as the Basel, Switzerland-based company progresses four phase II trials, with key data readouts expected in 2025.
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Concept of business partnership
Inflammatory

Relation inks two GSK deals tackling osteoarthritis, fibrotic disease

Dec. 11, 2024
By Nuala Moran
Relation Therapeutics Ltd. has delivered the first commercial validation of its combined wet lab/in silico platform for homing in on disease-related genes in the thick of the genome, signing two collaboration agreements with GSK plc, with a potential value of $200 million per target.
Read More
Concept of business partnership

Relation inks two GSK deals tackling osteoarthritis, fibrotic disease

Dec. 10, 2024
By Nuala Moran
Relation Therapeutics Ltd. has delivered the first commercial validation of its combined wet lab/in silico platform for homing in on disease-related genes in the thick of the genome, signing two collaboration agreements with GSK plc, with a potential value of $200 million per target.
Read More
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