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Home » Authors » Randy Osborne

Articles by Randy Osborne

Roche TIGIT bid wows ASCO, upper rung in lung; Fc main key?

June 2, 2020
By Randy Osborne
A key opinion leader (KOL) consulted by SVB Leerink deemed Roche Holding AG’s anti-TIGIT drug results “really huge” and “quite amazing,” affirming the Basel, Switzerland-based firm’s lead in the field. The phase II data from the study known as Cityscape rolled out at the virtual American Society of Clinical Oncology (ASCO) meeting.
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Howard Burris, former president, ASCO

ASCO20: ‘Computer virus’ takes new meaning, ASCO participants not bugged

June 1, 2020
By Randy Osborne
Gone from the American Society of Clinical Oncology (ASCO) meeting were the packed halls of McCormick Place in Chicago and the excited bustle of scientists reacquainting with each other at the always data-rich event. ASCO’s annual confab, held online because of the COVID-19 pandemic, still managed to pull off what former president Howard Burris called a “resounding success,” with about 40,000 registrants, similar to previous years.
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ASCO20: Allogene CAR T ‘shelf life’ mulled as early phase I results rival autologous

June 1, 2020
By Randy Osborne
Allogene Therapeutics Inc. investors will have to wait for an update in the second half of this year to find out more about whether off-the-shelf ALLO-501 can durably stand up to autologous CAR T-cell therapies, but early data disclosed at the American Society of Clinical Oncology meeting is creating buzz in the meantime.
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ASCO20: Adaptimmune updates work at T-cell frontier; SPEAR in high gear, ASCO hears

June 1, 2020
By Randy Osborne
Shares of Adaptimmune Therapeutics plc (NASDAQ:ADAP) rocketed to $11.07 Friday, up $127% or $6.21, on updated data rolled out at the American Society of Clinical Oncology (ASCO) meeting, held virtually this year.
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Lung cancer illustration

Just Adaurable: Astrazeneca’s phase III Tagrisso data captivate at ASCO

May 29, 2020
By Randy Osborne
Astrazeneca plc’s Tagrisso (osimertinib) seems poised to become standard of care in the adjuvant setting for early stage (IB, II and IIIA) EGFR-mutated non-small-cell lung cancer (NSCLC), thanks to phase III data from the study called Adaura, made public at the American Society of Clinical Oncology (ASCO) meeting.
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ASCO analysis weighs cancer plus COVID-19 double whammy

May 28, 2020
By Randy Osborne
The impact of COVID-19 is being felt at the American Society of Clinical Oncology (ASCO) annual meeting as much as anywhere else, typically held at McCormick Place in Chicago but this year conducted virtually because of the pandemic.
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Hands holding gears

Gold, plated: Arcus covenant with Gilead commands potential $2B chestful

May 27, 2020
By Randy Osborne
Arcus Biosciences Inc. “brings the milk without [Gilead Sciences Inc.] having to buy the whole cow” is the way one analyst characterized the pair’s 10-year cancer immunotherapy deal, which could be worth as much as $2 billion, and some may have detected downside for Arcus, as shares (NYSE:RCUS) closed May 27 at $27.05, down $6.49, or 19%. Foster City, Calif.-based Gilead is paying Arcus, of Hayward, Calif., $175 million up front, shelling out a $200 million equity investment, and pledging potentially $1.6 billion or more in the form of R&D support, opt-in cash and milestone payments.
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Gilead makes Arcus pact official: 10-year tie-up worth as much as $2B

May 27, 2020
By Randy Osborne

Wall Street quick to laud efgartigimod, phase III MG marquis

May 26, 2020
By Randy Osborne
Argenx SE’s later-stage effort with antibody fragment efgartigimod in generalized myasthenia gravis (gMG) was designed with guidance from the phase II trial that showed 75% of patients had a durable response of at least six weeks.
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Person holding knee, joint pain

Plan with the golden arm deals Navidea phase II imaging win in RA

May 22, 2020
By Randy Osborne
Navidea Biopharmaceuticals Inc. CEO Jed Latkin said positive findings from the second interim analysis of the phase IIb study called NAV3-31 “were certainly better than what we were looking for” and will “make our partnering discussions a lot more interesting.”
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