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Home » Authors » Randy Osborne

Randy Osborne

Articles

ARTICLES

Time-2b skeptical? Aerpio NPDR data hobble shares; investigate kidney upside

March 19, 2019
By Randy Osborne
Aerpio Pharmaceuticals Inc.'s phase IIb data with AKB-9778 in moderate to severe nonproliferative diabetic retinopathy (NPDR) failed to provide betterment relative to the phase IIa experiment in diabetic macular edema (DME), but CEO Stephen Hoffman noted that the findings were "hot off the press" and the company needs to conduct an internal review, with more detail to come at a scientific meeting.
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Incoming taxanes deduct side effects; Odonate oral bid audit reveals promise

March 18, 2019
By Randy Osborne
The prospects of an oral taxane chemotherapy – providing similar efficacy to intravenous (I.V.) with a better toxicity profile – have drawn players to the field that include Odonate Therapeutics Inc. and Athenex Inc., the latter with a phase III trial fully enrolled and the former with a late-stage experiment expected to finish sign-ups in the second half of this year.
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Sanofi dengue vaccine hit with divided adcom ballot; testing, safety key disputes

March 13, 2019
By Randy Osborne
As the Philippine Department of Justice (PDOJ) said it found probable cause to indict Sanofi SA and government officials over deaths caused by the Paris-based pharma giant's dengue vaccine, the FDA's Vaccines and Related Biological Products Advisory Committee (VRBPAC) reviewed the BLA for the product in an uneventful session.
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Assay can you see? Effort in diabetes active, Zafgen discloses holdup in PWS

March 13, 2019
By Randy Osborne
Zafgen Inc. CEO Jeffrey Hatfield said the firm has backup compounds for ZGN-1258 to treat Prader-Willi syndrome (PWS) and "remains committed" to the condition. "We're going to evaluate all of our options to try and unlock potential value we see in methionine aminopeptidase 2 [MetAP2] inhibition for this terrible disease."
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Bacteria in crosshairs, Snipr nets $50M series A for dual effort in CRISPR

March 12, 2019
By Randy Osborne
Snipr Biome ApS was "flying a little bit under the radar" until the company had "something worth listening to," CEO Christian Grondahl told BioWorld, and the day for talking arrived with the Copenhagen-based company raising $50 million in series A cash.
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Series A pumps $11M into Cerebral's epilepsy efforts; drug-device IND just ahead

March 11, 2019
By Randy Osborne

Series A pumps $11M into Cerebral's epilepsy efforts; drug-device IND just ahead

March 11, 2019
By Randy Osborne
Cerebral Therapeutics Inc. CEO Dan Abrams told BioWorld that his firm's closing of the $7.8 million extension to its series A financing by Granite Point Capital Management LP and Vivo Capital LLC should "allow us to do a substantial phase II trial" that will bring an epilepsy drug-device combo therapy to the next level.
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Sanofi dengue vaccine hit with divided adcom ballot; testing, safety key disputes

March 8, 2019
By Randy Osborne
As the Philippine Department of Justice (PDOJ) said it found probable cause to indict Sanofi SA and government officials over deaths caused by the Paris-based pharma giant's dengue vaccine, the FDA's Vaccines and Related Biological Products Advisory Committee (VRBPAC) reviewed the BLA for the product in an uneventful session.
Read More

Beetles sing money tune as Verrica result punches cantharidin ticket to ride

March 7, 2019
By Randy Osborne

Raise high the roof Beam; backers see more upside, add $135M series B round

March 7, 2019
By Randy Osborne
Beam Therapeutics Inc. CEO John Evans told BioWorld that the company's $135 million series B influx – following sooner than some expected the $87 million series A raise last May – is meant to "make sure that resources aren't the limiting factor" in pushing along the company's next-generation CRISPR technologies, expanding the pipeline of base editing programs, and adding to the firm's scientific and technical leadership.
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View All Articles by Randy Osborne

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