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Home » Authors » Randy Osborne

Randy Osborne

Articles

ARTICLES

Rows of red and blue game pieces with hybrid center piece

Increased Avidity in DM1 space as players jostle for position

March 7, 2022
By Randy Osborne

As Neubase Therapeutics Inc. gears up to unveil preclinical data from its myotonic dystrophy type 1 (DM1) effort during the MDA Clinical & Scientific Conference later this month, investors are watching other programs moving through pipelines – but none of the research, except for that underway by Avidity Biosciences Inc., has entered the clinic.


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Handshake, businessmen holding dollar sign, lightbulb

Divestiture unrest as Viatris sheds biosimilars in $3.34B

March 1, 2022
By Randy Osborne
Biocon Ltd. said its subsidiary Biocon Biologics Ltd. has agreed to buy out partner Viatris Inc., bringing aboard the latter’s biosimilars business, for $3.34 billion.
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COVID-19 vaccine and syringe with flag of China

Mitsubishi, GSK harvest plant-based COVID-19 vaccine win in Canada

March 1, 2022
By Randy Osborne
With the first global approval by Health Canada in hand, Medicago Inc. aims to provide 20 million doses this year of Covifenz – which itself represents another first, as a plant-originated, virus-like particle, recombinant, adjuvanted COVID-19 vaccine. “Hopefully, if all goes well, we’ll be able to do it faster than the last day of the last month” of the year, said Brian Ward, medical officer of Quebec City-based Medicago, a unit of Mitsubishi Tanabe Pharma Corp., which partnered on Covifenz with Glaxosmithkline plc (GSK).
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Divestiture unrest as Viatris sheds biosimilars in $3.34B deal

Feb. 28, 2022
By Randy Osborne
Biocon Ltd. said its subsidiary Biocon Biologics Ltd. has agreed to buy out partner Viatris Inc., bringing aboard the latter’s biosimilars business, for $3.34 billion, including cash of $2.34 billion and compulsorily convertible preference shares (CCPS) in BBL, valued at $1 billion.
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Acquisition target

They conduit: Channel takeover plus BMS deal ‘appropriate’ spend, says Biohaven CEO

Feb. 25, 2022
By Randy Osborne
Biohaven Pharmaceutical Holding Co. Ltd. signed a deal that could be worth more than $1 billion to take over Channel Biosciences LLC, a subsidiary of Knopp Biosciences LLC, and its Kv7 channel targeting platform. A key part of the deal is BHV-7000, formerly known as KB-3061, described as a potent activator of Kv7.2 and Kv7.3, key subunits involved in neuronal signaling and in regulating the hyperexcitable state in epilepsy. The compound is expected to enter clinical investigation this year, with focal epilepsy as the lead indication.
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Mitsubishi, GSK harvest plant-based COVID-19 vaccine win in Canada

Feb. 24, 2022
By Randy Osborne
With the first global approval by Health Canada in hand, Medicago Inc. aims to provide 20 million doses this year of Covifenz – which itself represents another first, as a plant-originated, virus-like particle, recombinant, adjuvanted COVID-19 vaccine. “Hopefully, if all goes well, we’ll be able to do it faster than the last day of the last month” of the year, said Brian Ward, medical officer of Quebec City-based Medicago, a unit of Mitsubishi Tanabe Pharma Corp., which partnered on Covifenz with Glaxosmithkline plc (GSK).
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Kodiak moment spoiled, shares bearish as AMD study fails to Dazzle

Feb. 23, 2022
By Randy Osborne
Kodiak Sciences Inc. shares (NASDAQ:KOD) closed at $9.86, down $40.49, or 80.42% after the firm unveiled top-line data from its randomized, double-masked, active comparator-controlled phase IIb/III trial testing KSI-301, an antibody biopolymer conjugate, in treatment-naïve subjects with wet age-related macular degeneration (AMD).
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Wall Street high on LSD1; mid-stage, early trips underway

Feb. 22, 2022
By Randy Osborne
Jubilant Therapeutics Inc. started 2022 with an IND clearance for JBI-802, its oral, selective dual inhibitor of lysine-specific demethylase 1 (LSD1) and HDAC6, setting up a year that could be important for LSD1 in the hands of others as well.
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Thyroid anatomy

Ascendis rising in HPT, Natpara comparator off base?

Feb. 18, 2022
By Randy Osborne
Phase III data are due any day from Ascendis Pharma A/S, and Wall Street’s thoughts have turned to hypoparathyroidism (HPT), an indication fraught with questions in recent years.
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Skin irritation on hands

Balance beam: Third Harmonic’s start value high in KIT, scores $105M series B

Feb. 16, 2022
By Randy Osborne
Third Harmonic Bio Inc. CEO Natalie Holles said the company’s $105 million in series B money will push THB-001 – a first-in-class, highly selective, oral inhibitor of wild-type KIT – “well past the first proof-of-concept study in inducible urticaria [hives].”
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View All Articles by Randy Osborne

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