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Home » Authors » Anette Breindl

Anette Breindl

Articles

ARTICLES

Mutation hotspots don't always signal drivers

Sep. 20, 2019
By Anette Breindl
In the world of cancer genomics, mutational hotspots and cancer drivers are used somewhat interchangeably. "It was common knowledge... that if you see a site [mutated] in many cancers, that site is a driver," Gad Getz told BioWorld. But Getz, who is director of the Cancer Genome Computational Analysis Group at the Broad Institute of MIT and Harvard, and his team argue that the conventional wisdom is incorrect.
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Study shows CAR T cells can reverse cardiac fibrosis

Sep. 13, 2019
By Anette Breindl
CAR T cells engineered to target fibroblast activating protein (FAP) could reverse cardiac fibrosis and restore cardiac function in mice, researchers have reported in the Sept. 12, 2019, issue of Nature.
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Super cool study shows organ life can be extended

Sep. 12, 2019
By Anette Breindl

Lasker Foundation honors Herceptin, vaccines, immunology

Sep. 11, 2019
By Anette Breindl
The 2019 Lasker Award winners were announced Tuesday, adding five researchers and GAVI, the Vaccine Alliance, to its roster of Laureates.
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Super cool study shows organ life can be extended

Sep. 10, 2019
By Anette Breindl
By preventing ice formation while cooling human livers below freezing, researchers have managed to extend the viable lifespan of donated livers threefold.
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Study partially rehabilitates telomerase in cancer

Sep. 9, 2019
By Anette Breindl
Telomerase's reputation is that it has an important role in maintaining the ability of stem cells to divide through maintaining telomeres, the structures at the tips of chromosomes that shorten with each replication cycle.
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Bench Press: BioWorld looks at translational medicine

Sep. 9, 2019
By Anette Breindl
Researchers at the University of California at San Diego have used a strategy of "rock-paper-scissors" to engineer more durable synthetic circuits into bacteria. 
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Entyvio for HIV control flops in clinical trial, replication studies

Sep. 6, 2019
By Anette Breindl
Three separate research teams have failed to replicate a 2016 primate study showing that treatment with a primate version of monoclonal antibody Entyvio (vedolizumab, Takeda Pharmaceutical Co. Ltd.), led to prolonged suppression of viremia in SHIV-infected monkeys. 
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Bench Press: BioWorld looks at translational medicine

Sep. 3, 2019
By Anette Breindl
Researchers at the Christian Albrechts University of Kiel and the MRC London Institute of Medical Science have developed a way to screen four-way interactions between genetically simple hosts, their microbiome, nutrients and drugs. 
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Autologous iPSCs can lead to immune response

Aug. 29, 2019
By Anette Breindl
From the research point of view, making induced pluripotent stem cells (iPSCs) is perhaps not exactly easy, but routine rather than a heroic effort.
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View All Articles by Anette Breindl

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