Two gene expression signatures in blood samples of pregnant women could accurately assess the gestational age of the fetus, and predict which pregnancies would end in preterm birth, respectively.
Early life complications (ELCs) can double the risk of developing schizophrenia, an effect that is greater than that of any common genetic variant. Researchers from the Lieber Institute for Brain Development have discovered that such ELCs affected gene expression in the placenta, and they did so in different ways in the placentas of male and female fetuses.
In the quest to bring chimeric antigen receptor (CAR) T cells to new groups of patients, a lot of work has been focused on engineering the CAR T cells themselves.
Multiple nanorobots with single functions have been developed in recent years. Now, researchers have created a single nanorobot with multiple functions.
In medicine, too, there is no free lunch – effective therapies come with side effects. But two new studies could make lunch cheaper for patients treated with chimeric antigen receptor (CAR) T cells. Researchers at the San Raffaele Hospital in Milan, Italy, and the Memorial Sloan Kettering Cancer Center (MSKCC) have gained new insights into the causes of cytokine release syndrome (CRS) and neurotoxicity, the two most serious forms of toxicity that are associated with CAR T cells.
Researchers from the University of California at Los Angeles and Duke University have developed an implantable gel that could stimulate first blood vessel formation, and then brain regeneration, after stroke.
