Twenty years after the first, exclusively white human genomes were fully sequenced, science finds itself in the same position as the rest of society: with the uncomfortable realization that old inequalities are often morphing, rather than disappearing.
Keeping you up to date on recent developments in neurology, including: Fast brainwave oscillations identify, localize epileptic brain; Sleep biomarkers linked to neurodegenerative disease; Autophagy chaperone targets aggregation-prone proteins.
The enzyme proprotein convertase subtilisin/kexin type 9 (PCSK9) plays a major role in the regulation of blood LDL cholesterol levels. Now, new research shows that targeting PCSK9 may also potentiate checkpoint blockade.
Senti Biosciences Inc. stands to receive more than $645 million in up-front, opt-in and milestone payments through a new collaboration and option agreement with Spark Therapeutics Inc.
Cachexia, Teresa Zimmers told the audience at the Annual Meeting of the American Association for Cancer Research (AACR), is "woefully understudied for the outsized impact it has on cancer patients." The condition, which is currently defined as weight loss and muscle wasting, is the direct cause of death in an estimated 25% to 30% of cancer patients. But it is the main subject of only 0.1% of research papers and 0.2% of clinical trials.
Keeping you up to date on recent developments in oncology, including: Popcorn-like gold nanofilms for detection of miRNA in cancer; Myeloid cells differ in primary and recurrent glioblastoma; Premetastatic niche is prepared via leaky gut in colorectal cancer; Brain metastases of breast cancer depend on fatty acid synthesis.
Researchers at the J. Craig Venter Institute and the National Institute of Standards and Technologies have identified seven genes that are indispensable in order for the "minimal genome" or JCV3.0 cell to divide into two equal daughter cells.
Keeping you up to date on recent developments in neurology, including: DBS shows promise in treating OCD patients with comorbidities; COVID-19-associated seizures linked to higher risk of death; Antibodies could make things worse in neurodegeneration; Ultrarare variants give insights into schizophrenia.
