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Home » Authors » Anette Breindl

Anette Breindl

Articles

ARTICLES

ENCODE project illustration
Phase IV now underway

Data reported from ENCODE phase III

July 29, 2020
By Anette Breindl
Researchers from the Encyclopedia of DNA Elements (ENCODE) consortium reported data from the third phase of the project. Phase III data, which were published in more than a dozen papers in Nature and its sister journals on July 29, 2020, consisted of 6,000 experiments performed on around 1,300 samples.
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Newco news

Starvation safety switch could make cell therapies safer

July 28, 2020
By Anette Breindl
By deleting the gene for uridine monophosphate synthetase (UMPS), an enzyme in the pathway for uridine synthesis, researchers have made cells, including embryonic stem cells and T cells, dependent on dietary uridine. The work, which was published in the July 13, 2020, online issue of Nature Biotechnology, adds a new potential way of controlling cell therapies.
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Silhouette with keyhole

Alzheimer’s blood test could improve trials, help find treatments

July 28, 2020
By Anette Breindl
CYBERSPACE – Data presented at the virtual 2020 Alzheimer's Association International Conference (AAIC) and reported in the July 28, 2020, online issue of the Journal of the American Medical Association (JAMA) demonstrated that blood levels of phosphorylated tau-217 (Ptau-217) did as well as cerebrospinal (CSF)- and PET-based biomarkers, and significantly better than other blood-based biomarkers, at discriminating individuals with Alzheimer’s disease (AD) from those with other neurodegenerative disorders.
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Cells, DNA illustration
Newco news

Starvation safety switch could make cell therapies safer

July 27, 2020
By Anette Breindl
By deleting the gene for uridine monophosphate synthetase (UMPS), an enzyme in the pathway for uridine synthesis, researchers have made cells, including embryonic stem cells and T cells, dependent on dietary uridine. The work, which was published in the July 13, 2020, online issue of Nature Biotechnology, adds a new potential way of controlling cell therapies.
Read More
Electrical activity of the brain
EEGs and endotypes

From cells to cortices, ways to improve neurological disease classification

July 24, 2020
By Anette Breindl
Cancer treatment has been transformed, at its root, by a transformational change in how it is classified. Those successes have not escaped the notice of researchers in other areas of biomedicine, and diseases including heart failure, asthma and polycystic ovarian syndrome are being looked at with an eye to subdividing them in ways that brings diagnostics into the molecular era.
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Normal vision vs. vision with AMD

Bench Press for July 24, 2020

July 24, 2020
By Anette Breindl
BioWorld looks at translational medicine, including: Structural study gives insight into plaque formation; Studying labor identifies new pain mechanism; AHR inhibition suppresses Zika infection; iPSCs find best therapy for Best disease.
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BioWorld MedTech’s Diagnostics Extra for July 23, 2020

July 23, 2020
By Meg Bryant and Anette Breindl
Keeping you up to date on recent developments in diagnostics, including: Scaling patient stratification in EHRs using deep learning; Improving prognosis of pancreatic cancer; Mitochondria, interneurons, cognition link explored.
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Electrical activity of the brain
EEGs and endotypes

From cells to cortices, ways to improve neurological disease classification

July 23, 2020
By Anette Breindl
Cancer treatment has been transformed, at its root, by a transformational change in how it is classified. These days, which organ a tumor arises in is often less important than its molecular drivers, which can be sensitive either to specific targeted treatments, or increase the chance that a tumor will respond to immunotherapy. Those successes have not escaped the notice of researchers in other areas of biomedicine, and diseases including heart failure, asthma and polycystic ovarian syndrome are being looked at with an eye to subdividing them in ways that brings diagnostics into the molecular era. Nowhere do those changes have greater potential than in disorders of the brain – in part because there is nowhere much to go but up as far as classifying neurological diseases goes.
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BioWorld MedTech’s Oncology Extra for July 21, 2020

July 21, 2020
By Mark McCarty and Anette Breindl
Keeping you up to date on recent developments in oncology, including: Artificial intelligence plus dual-stain testing beats cytology for cervical cancer detection; Protein degradation system targeted to KRAS; Preventing T-cell rejection; Beating cytokine toxicity one layer at a time.
Read More
Human X Chromosome Sequence puzzle

Bench Press for July 17, 2020

July 17, 2020
By Anette Breindl

BioWorld looks at translational medicine, including: X chromosome is finished; Protein degradation system targeted to KRAS; Bacteriophages find, fight microbiome’s dark side; Preventing T-cell rejection;  Mitochondria, interneurons, cognition link explored.


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View All Articles by Anette Breindl

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