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Home » Authors » Brian Orelli

Articles by Brian Orelli

23andme saliva collection kit

Regeneron plans to buy 23andme from bankruptcy for $256M

May 19, 2025
By Brian Orelli
No Comments
Regeneron Pharmaceuticals Inc. was the successful bidder for 23andme Holding Co.’s personal genome service, total health and research services business lines, including its biobank and associated assets, in the bankruptcy auction to sell 23andme's assets.
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Therini Bio locks in another $39M for its fibrin-targeting immunotherapies

May 16, 2025
By Brian Orelli
No Comments
Therini Bio raised an additional $39 million in its series A financing round, bringing the total for the round to $75 million. The capital will be used to advance its fibrin-targeting immunotherapies for neurodegenerative diseases.
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Glycomine snags $115M to advance its PMM2-CDG treatment

April 17, 2025
By Brian Orelli
Glycomine Inc. secured $115 million in a series C financing round to support the advancement of GLM-101 into a phase IIb study in patients with phosphomannomutase-2 congenital disorder of glycosylation (PMM2-CDG).
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Newco news

Hillstar launches with $67M series A to target TRBV9+ T cells

March 25, 2025
By Brian Orelli
Hillstar Bio came out of stealth mode, announcing a $67 million series A financing round with investors including Droia Ventures, Frazier Life Sciences, Novo Holdings A/S and Lifearc Ventures.
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Biocom AI panel

Biocom 2025: The quickly evolving AI landscape

Feb. 26, 2025
By Brian Orelli
A panel at Biocom California’s 15th Annual Global Life Science Partnering & Investor Conference covered the emerging use of artificial intelligence (AI) to discover and develop drugs. “We’re in a very different place than we were five years ago, or even three years ago, even two years ago, from our ability to harness AI to make advances,” Marc Tessier-Lavigne, CEO of South San Francisco-based Xaira Therapeutics Inc., told the audience, adding that the development is actually accelerating.
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Windward Bio launches with an in-licensed asset for asthma and COPD

Jan. 10, 2025
By Brian Orelli
Windward Bio AG was established with plans to both license a drug and establish wet labs to create an internal pipeline of drug candidates. SR One, Omega Funds, RTW Investments, Qiming Venture Partners, Quan Capital and Pivotal Bioventure Partners funded the Basel, Switzerland-based company’s $200 million series A financing round.
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Imbruvica capsules and packaging

BTK inhibitor potential highlighted at ASH 2024

Dec. 10, 2024
By Brian Orelli
At the 66th American Society of Hematology Annual Meeting, a plethora of companies presented clinical trial data highlighting their drugs targeting Bruton tyrosine kinase (BTK) in patients with blood cancers.
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Red blood cells on blue background

ASH 2024: Agios’ mitapivat checks off efficacy; liver toxicity a concern

Dec. 9, 2024
By Brian Orelli
Agios Pharmaceuticals Inc. is learning the hard way the downside of having a pipeline in a product. When a side effect crops up, investors are likely to worry that it may affect the potential of the drug in the numerous diseases the drug could potentially treat.
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Diverse multicultural group of people

Biocom: Advice for adding diversity in clinical trials

Dec. 4, 2024
By Brian Orelli
Methods that may work well for recruiting and retaining white patients for clinical trials may need to be adjusted to maximize the involvement of patients from other ethnic backgrounds. At Biocom California’s Let’s Talk About series, panelists discussed the benefits and best practices for adding diversity to clinical trials.
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Liver

The Liver Meeting: A mashup of MASH data

Nov. 19, 2024
By Brian Orelli
Advertisements for Rezdiffra (resmetirom, Madrigal Pharmaceuticals Inc.), which was approved by the U.S. FDA in March 2024, adorned the lobby of The Liver Meeting 2024 being held at the San Diego Convention Center as well as the trolley stop across the street and other areas that doctors attending the meeting might be swayed. But inside the ballrooms of the convention center, companies were making presentations of data from clinical trials testing their drugs in patients with metabolic dysfunction-associated steatohepatitis (MASH) in hopes of potentially competing with Rezdiffra in a few years.
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