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Home » Authors » Jennifer Boggs

Articles by Jennifer Boggs

Two arrows in opposite directions

Abbvie drops full CD47 collaboration, as I-Mab pushes ahead with phase III

Sep. 26, 2023
By Jennifer Boggs
I-Mab Biopharma Co. Ltd. has regained full rights to its CD47 antibody program from Abbvie Inc., including lemzoparlimab, the most advanced candidate. The move, disclosed in a Sept. 22 U.S. SEC filing, eliminates the potential $1.295 billion in milestones associated with the amended collaboration deal signed in 2022.
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Two arrows in opposite directions

Abbvie drops full CD47 collaboration, as I-Mab pushes ahead with phase III

Sep. 25, 2023
By Jennifer Boggs
I-Mab Biopharma Co. Ltd. has regained full rights to its CD47 antibody program from Abbvie Inc., including lemzoparlimab, the most advanced candidate. The move, disclosed in a Sept. 22 U.S. SEC filing, eliminates the potential $1.295 billion in milestones associated with the amended collaboration deal signed in 2022.
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Leukemia illustration

FDA grants broad label for GSK’s momelotinib in myelofibrosis with anemia

Sep. 18, 2023
By Jennifer Boggs and Caroline Richards
Five years after Gilead Sciences Inc. gave up on momelotinib in the wake of two phase III failures in myelofibrosis, the JAK1/2 and ACVR1 inhibitor has found its way to the market in the hands of GSK plc. Branded Ojjaara, the drug gained U.S. FDA approval for use in intermediate- or high-risk myelofibrosis patients with anemia regardless of prior administration with JAK inhibitors such as Jakafi (ruxolitinib, Incyte Corp.).
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Various pills laid across a target
Neurology/Psychiatric

Precision med startup Actio draws $55M series A investment

Sep. 13, 2023
By Jennifer Boggs
“From one to many” is how Actio Biosciences Inc. describes its approach to drug development. The firm emerged with a $55 million series A financing and an eye for biological targets found in both rare and common diseases, starting with TRPV4, a target associated with Charcot-Marie-Tooth disease type 2C and other bone diseases.
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Dollar sign inside light bulb
Newco news

Precision med startup Actio draws $55M series A investment

Sep. 12, 2023
By Jennifer Boggs
“From one to many” is how Actio Biosciences Inc. describes its approach to drug development. The firm emerged with a $55 million series A financing and an eye for biological targets found in both rare and common diseases, starting with TRPV4, a target associated with Charcot-Marie-Tooth disease type 2C and other bone diseases.
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Optogenetics illustration

Shape, Otsuka ink $1.5B gene therapy alliance targeting ocular diseases

Sep. 8, 2023
By Jennifer Boggs
In its second big pharma deal to date, Shape Therapeutics Inc. drew Otsuka Pharmaceutical Co. Ltd. to the table in a potential $1.5 billion-plus collaboration initially aimed at developing gene therapies for ocular diseases. The multitarget agreement, which includes options for additional targets and tissue types, will combine Shape’s AI-driven adeno-associated virus (AAV) platform and Otsuka’s expertise in ophthalmology to develop intravitreally delivered AAV therapies.
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Doctor examining child's leg

Amo plans regulatory talks for AMO-02 on back of pivotal CDM1 data

Sep. 6, 2023
By Jennifer Boggs
While an “unexpected placebo effect” marred its primary endpoint, the pivotal phase II/III study testing AMO-02 (tideglusib) showed clinically significant benefits across a range of functional and objective assessments, according to developer Amo Pharma Ltd., which is prepping to meet with regulators to discuss potential approval for use in children and adolescents with congenital myotonic dystrophy type 1 (CDM1), an ultra-rare subtype of myotonic dystrophy type 1 for which no treatment options are available.
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Promising Star formations draw investors in $90M oversubscribed series C

Sep. 5, 2023
By Jennifer Boggs
Star Therapeutics Inc. brought on board six new investors in its oversubscribed $90 million series C round, raising the company’s total funding to more than $190 million since its founding in 2018 to advance in-house drug discovery efforts via formation of portfolio companies. Since emerging from stealth in early 2022, Star has launched two aptly named companies, Electra Therapeutics Inc. and Vega Therapeutics Inc., with plans to unveil additional ventures arising from its antibody discovery efforts.
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Drug Design, Drug Delivery & Technologies

Faster than light drug discovery: Superluminal launches with $33M seed round

Sep. 4, 2023
By Jennifer Boggs
As its name suggests, Superluminal Medicines Inc. is aiming for speed. The startup, which closed a $33 million seed round led by RA Capital Management, is combining a biology-focused approach with a generative AI platform it says has the potential to create candidate-ready compounds in a matter of months, with its initial sights set on G protein-coupled receptor targets.
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Startup key, rocket icon
Newco news

Faster than light drug discovery: Superluminal launches with $33M seed round

Aug. 28, 2023
By Jennifer Boggs
As its name suggests, Superluminal Medicines Inc. is aiming for speed. The startup, which closed a $33 million seed round led by RA Capital Management, is combining a biology-focused approach with a generative AI platform it says has the potential to create candidate-ready compounds in a matter of months, with its initial sights set on G protein-coupled receptor targets.
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