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Home » Authors » John Fox

Articles by John Fox

Novel treatment for tumors with DNA repair deficiencies

July 14, 2016
By John Fox
HONG KONG – A Korean study has identified a novel small-molecule chemotherapy that offers the potential to be an improved treatment option for patients with tumors having a DNA mismatch repair (MMR) deficiency, which do not respond to conventional chemotherapies. Research was published in the July 5, 2016, early online edition of Cancer Research.
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Novel treatment for tumors with DNA repair deficiencies

July 13, 2016
By John Fox
HONG KONG – A Korean study has identified a novel small-molecule chemotherapy that offers the potential to be an improved treatment option for patients with tumors having a DNA mismatch repair (MMR) deficiency, which do not respond to conventional chemotherapies. Research was published in the July 5, 2016, early online edition of Cancer Research.
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Mobilizing innate, adaptive immune response in cancer

July 6, 2016
By John Fox
HONG KONG — A novel vaccine-based cancer treatment strategy, which can stimulate both an innate and an adaptive immune response, has been developed by scientists at the RIKEN Center for Integrative Medical Sciences (IMS) in Yokohama, Japan. That finding may ultimately result in more successful cancer treatments.
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Mobilizing innate, adaptive immune response in cancer

July 6, 2016
By John Fox
HONG KONG – A novel vaccine-based cancer treatment strategy, which can stimulate both an innate and an adaptive immune response, has been developed by scientists at the RIKEN Center for Integrative Medical Sciences (IMS) in Yokohama, Japan. That finding may ultimately result in more successful cancer treatments.
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Cancer stem cell vaccine shown optimal in adjuvant setting

June 30, 2016
By John Fox
HONG KONG – Dendritic cell-based vaccine strategies that target cancer stem cells (CSCs) may be most effective when they are used in the adjuvant setting, according to findings of a new U.S./China collaborative preclinical study in mice reported in Cancer Research.
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Cancer stem cell vaccine shown optimal in adjuvant setting

June 29, 2016
By John Fox
HONG KONG – Dendritic cell-based vaccine strategies that target cancer stem cells (CSCs) may be most effective when they are used in the adjuvant setting, according to findings of a new U.S./China collaborative preclinical study in mice reported in the June 20, 2016, early online edition of Cancer Research.
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Potential new breast cancer prevention target identified in BRCA1 carriers

June 22, 2016
By John Fox
HONG KONG – New research has identified a targetable new pathway in a proposed cell-of-origin population in breast cancer-susceptible BRCA1 gene mutation carriers, implicating RANKL blockade as a promising strategy for the prevention of breast cancer.
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Potential breast cancer prevention target ID'd in BRCA1 carriers

June 22, 2016
By John Fox
HONG KONG – New research has identified a targetable new pathway in a proposed cell-of-origin population in breast cancer-susceptible BRCA1 gene mutation carriers, implicating RANKL blockade as a promising strategy for the prevention of breast cancer.
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Japanese substudy of ALEX reports interim data

June 16, 2016
By John Fox
HONG KONG – Alecensa (alectinib, Genentech/Roche AG) has been shown to be safe and effective in Asian patients, having shown superiority to the ALK Inhibitor Xalkori (crizotinib, Pfizer Inc.), in a phase III trial as a first-line treatment in Japanese patients with advanced or recurrent ALK-positive non-small-cell lung cancer (NSCLC).
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Parasites worm their way into arthritis treatment

June 10, 2016
By John Fox
HONG KONG – The findings of a new collaborative study by Chinese and German scientists suggest that activation in mice of a specific type of immune response, known as a Type 2 (Th2) response, using parasitic worm-derived stimuli, could clear the way to the development of new treatments for rheumatoid arthritis (RA).
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