• Sign In
  • Sign Out
  • My Account
Subscribe
  • BioWorld
  • BioWorld MedTech
  • BioWorld Asia
  • BioWorld Science
  • Data Snapshots
  • Special reports
Clarivate
  • Data Snapshots
  • BioWorld
  • BioWorld MedTech
  • Infographics: Dynamic digital data analysis
  • Special reports
  • Infographics: Dynamic digital data analysis
  • Trump administration impacts
  • Biopharma M&A scorecard
  • BioWorld 2024 review
  • BioWorld MedTech 2024 review
  • BioWorld Science 2024 review
  • Women's health
  • China's GLP-1 landscape
  • PFA re-energizes afib market
  • China CAR T
  • Alzheimer's disease
  • Israel
  • Rise of obesity
  • Radiopharmaceuticals
  • Biosimilars
  • Aging
  • IVDs on the rise
  • Coronavirus
  • Artificial intelligence

BioWorld. Link to homepage.

Clarivate
  • BioWorld
  • BioWorld MedTech
  • BioWorld Asia
  • BioWorld Science
  • Data Snapshots
    • BioWorld
    • BioWorld MedTech
    • Infographics: Dynamic digital data analysis
  • Special reports
    • Infographics: Dynamic digital data analysis
    • Trump administration impacts
    • Biopharma M&A scorecard
    • BioWorld 2024 review
    • BioWorld MedTech 2024 review
    • BioWorld Science 2024 review
    • Women's health
    • China's GLP-1 landscape
    • PFA re-energizes afib market
    • China CAR T
    • Alzheimer's disease
    • Israel
    • Rise of obesity
    • Radiopharmaceuticals
    • Biosimilars
    • Aging
    • IVDs on the rise
    • Coronavirus
    • Artificial intelligence

BioWorld. Link to homepage.

  • Sign In
  • Sign Out
  • My Account
Subscribe
Home » Authors » John Fox

John Fox

Articles

ARTICLES

Cancer cell and DNA

Tumor suppressor p53 is inactivated by lncRNA

July 16, 2021
By John Fox
A long noncoding RNA (lncRNA), the RNA component of mitochondrial RNA-processing endoribonuclease, was shown to promote the growth and proliferation of colorectal cancer cells by inhibiting activity of the tumor suppressor protein p53 in a Chinese study led by oncologists Fudan University Shanghai Cancer Center.
Read More
Mammogram

Barcoding strategy tracks breast cancer metastases

July 14, 2021
By John Fox
A study led by researchers at the Olivia Newton-John Cancer Research Institute, La Trobe University, The Walter and Eliza Hall Institute, and the University of Melbourne has used a novel optical color-coding barcoded cancer cell tracking strategy to investigate metastatic heterogeneity in breast cancer.
Read More
Condensate

Condensate drugs block RSV replication in vivo

July 13, 2021
By John Fox
Targeting viral condensates could be a valuable strategy for developing fast-acting, specifically targeted drugs with a potential broad spectrum of activity against pathogenic viruses, including respiratory syncytial virus (RSV), by targeting proteins critical for condensate formation, according to an international collaborative study.
Read More
Cancer cell and DNA

Study casts further light on cancer immunotherapy

July 9, 2021
By John Fox
Translationally controlled tumor protein (TCTP) is an immunomodulator that initiates development of an inflammatory milieu in the tumor microenvironment, where TCTP regulates high myeloid-derived suppressor cell activity, researchers have reported.
Read More
Neurons

Neurotrophic signaling deficiency exacerbates Alzheimer's risk factors

June 28, 2021
By John Fox
A deficiency in neurotrophic factor signaling has been shown to exacerbate environmental risk factors for the development of Alzheimer's disease pathogenesis in mice, according to a study reported in the June 22, 2021, online edition of the Proceedings of the National Academy of Sciences.
Read More
Cancer cells

Switching on prodrugs with radiotherapy shows promise

June 17, 2021
By John Fox
Local tumor conversion of a prodrug to an active agent using clinically relevant radiotherapy may herald a new era in targeted and directed cancer chemotherapy.
Read More
Liver

New target identified for acetaminophen liver injury

June 14, 2021
By John Fox
An international study led by scientists at Duke-NUS Medical School in Singapore has identified signaling for the cytokine IL-11 as representing a potential new therapeutic target for acetaminophen-induced liver injury in mouse models.
Read More
Brain teaser

Myelin renewal reverses AD cognitive dysfunction in mice

June 11, 2021
By John Fox
Researchers have demonstrated that enhancing myelin renewal in the brains of transgenic APP/PS1 mouse models of Alzheimer's disease (AD) can improve their task-related hippocampal activity.
Read More
Microscope and coronavirus illustration

MERS coronavirus study gives insights into zoonotic potential

June 8, 2021
By John Fox
An international study led by virologists at The University of Hong Kong has shown that geographically and genetically distinct Middle East respiratory syndrome coronaviruses (MERS-CoV) from Africa have lower replication competence in human and mouse lung than those from the ME.
Read More
Brain and neural networks

New PPARgamma agonist shows promise in neurodegenerative diseases

June 7, 2021
By John Fox
The new peroxisome proliferator-activated receptor gamma (PPARgamma) agonist leriglitazone (hydroxypioglizatone; Minoryx Therapeutics), has a better profile for treating neurodegenerative diseases, such as X-linked adrenoleukodystrophy (X-ALD), than similar drugs, including pioglitazone (Actos; Takeda).
Read More
View All Articles by John Fox

Popular Stories

  • Today's news in brief

    BioWorld
    BioWorld briefs for May 9, 2025.
  • Today's news in brief

    BioWorld MedTech
    BioWorld MedTech briefs for May 9, 2025.
  • US flag, stock market chart, White House

    100 days of uncertainty

    BioWorld
    The first 100 days of the Trump administration have been nothing short of chaotic, both in the U.S. and throughout the world. Shining a light through the...
  • AI generated, 3D rendering of protein degradation

    AACR 2025: Induced proximity strategy, beyond degraders

    BioWorld
    Targeted protein degradation has yet to notch its first approval. But with more than two dozen agents now in clinical trials, the strategy’s ultimate clinical...
  • NME Digest: Q1 2025

    BioWorld
    A quarterly dynamic table featuring new molecular entities (NMEs) revealed for the first time in current literature, at congresses and in company communications...
  • BioWorld
    • Today's news
    • Analysis and data insight
    • Clinical
    • Data Snapshots
    • Deals and M&A
    • Financings
    • Newco news
    • Opinion
    • Regulatory
    • Science
  • BioWorld MedTech
    • Today's news
    • Clinical
    • Data Snapshots
    • Deals and M&A
    • Financings
    • Newco news
    • Opinion
    • Regulatory
    • Science
  • BioWorld Asia
    • Today's news
    • Analysis and data insight
    • Australia
    • China
    • Clinical
    • Deals and M&A
    • Financings
    • Newco news
    • Regulatory
    • Science
  • BioWorld Science
    • Today's news
    • Biomarkers
    • Cancer
    • Conferences
    • Endocrine/Metabolic
    • Immune
    • Infection
    • Neurology/Psychiatric
    • Patents
  • More
    • About
    • Advertise with BioWorld
    • Archives
    • Article reprints and permissions
    • Contact us
    • Cookie policy
    • Copyright notice
    • Data methodology
    • Infographics: Dynamic digital data analysis
    • Podcasts
    • Privacy policy
    • Share your news with BioWorld
    • Staff
    • Terms of use
    • Topic alerts
Follow Us

Copyright ©2025. All Rights Reserved. Design, CMS, Hosting & Web Development :: ePublishing

BioWorld. Link to homepage.

Clarivate
  • BioWorld
  • BioWorld MedTech
  • BioWorld Asia
  • BioWorld Science
  • Data Snapshots
    • BioWorld
    • BioWorld MedTech
    • Infographics: Dynamic digital data analysis
  • Special reports
    • Infographics: Dynamic digital data analysis
    • Trump administration impacts
    • Biopharma M&A scorecard
    • BioWorld 2024 review
    • BioWorld MedTech 2024 review
    • BioWorld Science 2024 review
    • Women's health
    • China's GLP-1 landscape
    • PFA re-energizes afib market
    • China CAR T
    • Alzheimer's disease
    • Israel
    • Rise of obesity
    • Radiopharmaceuticals
    • Biosimilars
    • Aging
    • IVDs on the rise
    • Coronavirus
    • Artificial intelligence

BioWorld. Link to homepage.

  • Sign In
  • Sign Out
  • My Account
Subscribe