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Home » Authors » Elise Mak

Articles by Elise Mak

After Nasdaq, Sciclone turns to HKEX with $281M IPO to diversify pipeline

March 9, 2021
By Elise Mak
Four years after leaving the Nasdaq, Sciclone Pharmaceuticals Holdings Ltd. returned to the market March 3, issuing 116 million shares to raise HK$2.18 billion (US$281 million) on the Hong Kong Stock Exchange (HKEX). Shares were priced at HK$18.8 each.
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Target with off-center arrow

Bio-Thera terminates HER2 and Trop2 ADCs and PD-1 inhibitor programs

March 9, 2021
By Elise Mak
In an unusual move for a Chinese company, Bio-Thera Solutions Ltd. terminated the clinical development of its Trop2 antibody-drug conjugate (ADC), BAT-8003, and its PD-1 monoclonal antibody, BAT-1306, a month after it halted the phase III-stage HER2-ADC candidate BAT-8001.
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Target with off-center arrow

Bio-Thera terminates HER2 and Trop2 ADCs and PD-1 inhibitor programs

March 5, 2021
By Elise Mak
In an unusual move for a Chinese company, Bio-Thera Solutions Ltd. terminated the clinical development of its Trop2 antibody-drug conjugate (ADC), BAT-8003, and its PD-1 monoclonal antibody, BAT-1306, a month after it halted the phase III-stage HER2-ADC candidate BAT-8001.
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Stricter approval and faster reimbursement, executives urge at Two Sessions 2021

March 5, 2021
By Elise Mak
China’s most important annual government meetings, known as the “Two Sessions,” kicked off March 4 and biopharma executives that were also delegates to the National People's Congress (NPC) suggested that approval for trials should be stricter to avoid repetitive R&D and called for innovative drugs to get into the state insurance list – and to patients – faster.
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After Nasdaq, Sciclone turns to HKEX with $281M IPO to diversify pipeline

March 3, 2021
By Elise Mak
Four years after leaving the Nasdaq, Sciclone Pharmaceuticals Holdings Ltd. returned to the market March 3, issuing 116 million shares to raise HK$2.18 billion (US$281 million) on the Hong Kong Stock Exchange (HKEX). Shares were priced at HK$18.8 each.
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Ascletis joins Madrigal and Viking in global race for THR-β agonist for NASH

March 2, 2021
By Elise Mak
Liver disease specialist Ascletis Pharma Inc. said its nonalcoholic steatohepatitis (NASH)-focused subsidiary, Gannex Pharma Co. Ltd., will start global development of its oral THR-β agonist, ASC-41, after it obtained an IND approval from the FDA based on positive phase I data generated in China.
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Coronavirus and coins

Yisheng moves COVID-19 vaccine to clinic after $130M series B financing

March 2, 2021
By Elise Mak
Eight months after Beijing-based Yisheng Biopharma Co. Ltd. unveiled its recombinant protein vaccine candidate for COVID-19, YS-SC2-010, the company raised $130 million in a series B round to pave way for the vaccine to enter clinical trials in the second quarter of this year, the company’s CEO David Shao told BioWorld.
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Ascletis joins Madrigal and Viking in global race for THR-β agonist for NASH

Feb. 26, 2021
By Elise Mak
Liver disease specialist Ascletis Pharma Inc. said its nonalcoholic steatohepatitis (NASH)-focused subsidiary, Gannex Pharma Co. Ltd., will start global development of its oral THR-β agonist, ASC-41, after it obtained an IND approval from the FDA based on positive phase I data generated in China.
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Yisheng moves COVID-19 vaccine to clinic after $130M series B

Feb. 25, 2021
By Elise Mak
Eight months after Beijing-based Yisheng Biopharma Co. Ltd. unveiled its recombinant protein vaccine candidate for COVID-19, YS-SC2-010, the company raised $130 million in a series B round to pave way for the vaccine to enter clinical trials in the second quarter of this year, the company’s CEO David Shao told BioWorld.
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Drug vial and syringe

Clover bags $230M in series C, moves COVID-19 vaccine to phase II/III

Feb. 23, 2021
By Elise Mak
Chengdu-based Sichuan Clover Biopharmaceuticals Inc., known for its Trimer-Tag technology, raised $230 million in a series C financing round. The proceeds will, most notably, help it advance its COVID-19 vaccine candidate, S-Trimer (SCB-2019), to a global phase II/III trial by June. Following its $43 million series B round in December 2019, Clover said on Tuesday, Feb. 23, that it raised more than $400 million in the last 12 months. The company uses its Trimer-Tag technology platform to produce covalently-trimerized fusion proteins to develop protein-based vaccines and biologic cancer therapies.
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