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BioWorld - Friday, July 11, 2025
Home » Authors » Tamra Sami

Articles by Tamra Sami

Opthea in freefall after phase III fail in wet AMD

March 25, 2025
By Tamra Sami
Opthea Ltd. is considering its options after lead candidate sozinibercept (OPT-302) failed the phase III Coast trial in wet age-related macular degeneration (AMD). The global Coast phase III trial evaluated the efficacy and safety of intravitreally administered 2-mg sozinibercept every four or eight weeks in combination with 2-mg aflibercept every eight weeks after a loading phase for the treatment of wet AMD. The trial did not meet its primary endpoint of mean change in best corrected visual acuity from baseline to week 52.
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PhRMA takes aim at most of world for unfair trade practices

March 25, 2025
By Tamra Sami
In a move that echoes tariff threats from U.S. President Donald Trump, the Pharmaceutical Research and Manufacturers of America (PhRMA) lobby is taking aim at most of the world for unfair trade practices in its special 2025 Special 301 Report to the U.S. Trade Representative.
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Syneron Astrazeneca partnership

Astrazeneca invests in China: $8B in deals, $2.5B in R&D center

March 24, 2025
By Tamra Sami
Astrazeneca plc is investing heavily in China, signing two R&D deals, worth up to about $8 billion in up-front payments and milestones combined, with Chinese companies Harbour Biomed Ltd. and Syneron Bio, establishing a joint venture with Shenzhen Kangtai Biological Products Co. (Biokangtai) for vaccines, and creating a new R&D center in Beijing through another $2.5 billion investment.
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Opthea in freefall after phase III fail in wet AMD

March 24, 2025
By Tamra Sami
Opthea Ltd. is considering its options after lead candidate sozinibercept (OPT-302) failed the phase III Coast trial in wet age-related macular degeneration (AMD). The global Coast phase III trial evaluated the efficacy and safety of intravitreally administered 2-mg sozinibercept every four or eight weeks in combination with 2-mg aflibercept every eight weeks after a loading phase for the treatment of wet AMD. The trial did not meet its primary endpoint of mean change in best corrected visual acuity from baseline to week 52.
Read More
IV drips

Taimed’s long-acting HIV treatment offers daily ART alternative

March 20, 2025
By Tamra Sami
Taimed Biologics Inc.’s TMB-365/TMB-380 long-acting combination of broadly neutralizing antibodies regimen for HIV maintenance could reshape HIV treatment management, offering a viable alternative to daily combination antiretroviral therapy (cART), the Taipei-based company said after reporting on phase IIa results.
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Nandoun Abeysekera, founder and CEO, Avasa
Newco news

New Zealand’s Avasa develops world-first arterial coupler

March 19, 2025
By Tamra Sami
New Zealand med-tech startup Avasa Ltd. has developed an arterial coupler that could save surgeons 30 minutes in the operating room to better connect arteries.
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Ono scoops Ionis' hematology candidate sapablursen for up to $940M

March 18, 2025
By Tamra Sami
Ono Pharmaceutical Co. Ltd. struck a licensing deal with Ionis Pharmaceuticals Inc. for sapablursen, which is in phase II trials for polycythemia vera. Under terms, Osaka, Japan-based Ono gains an exclusive license to develop and commercialize sapablursen worldwide. Carlsbad, Calif.-based Ionis will be responsible for completing the ongoing phase II Imprssion study, while Ono will be responsible for subsequent development, regulatory filings and commercialization.
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Insilico Medicine CEO Alex Zhavoronkov with Insilico’s first bipedal humanoid AI Scientist called “Supervisor.”

Insilico advancing AI platform with $110M Asian-backed series E round

March 18, 2025
By Tamra Sami
Artificial intelligence (AI) drug developer Insilico Medicine raised $110 million in a series E round led by an Asian private equity fund, Value Partners Group, that will see Insilico advance its pipeline and AI platform developments.
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Visen announces HKD$603M Hong Kong IPO

March 18, 2025
By Tamra Sami
Visen Pharmaceuticals Co. Ltd. announced its initial public offering (IPO) on the Hong Kong Stock exchange (HKEX) to raise roughly HKD$603.3 million (US$77.6 million) to advance its pipeline of endocrinology assets.
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Colorized scanning electron microscope image of regulatory T cells and antigen-presenting cells.
Newco news

Japan’s Regcell launches in US with $45.8M to advance Treg platform

March 18, 2025
By Tamra Sami
Japanese-founded Regcell Inc. has raised $45.8 million and is redomiciling to the U.S. to accelerate clinical development of its pioneering regulatory T-cell (Treg) platform for autoimmune diseases and transplantation.
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