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Home » Authors » Tamra Sami

Articles by Tamra Sami

Coronavirus, lungs, hand holding stethoscope
Respiratory

Scientists discover gene associated with recovery responses in severe respiratory viral infections

Aug. 20, 2024
By Tamra Sami
Researchers have identified a gene associated with whether patients hospitalized with respiratory viral infections recover rapidly or face life-threatening complications. The gene has the potential to be used as a diagnostic tool or biomarker, which could help triage patients suffering from severe respiratory infections. Having such a biomarker would help clinicians in their early risk assessments to manage their intervention strategies.
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Australia flag with microscope, test tubes

Pfizer urges Australia to establish clear vision for life sciences

Aug. 19, 2024
By Tamra Sami
Pfizer Inc. is calling on the Australian government to establish priorities for the life sciences sector to attract more investment into research, clinical trials and manufacturing in Australia. The new report recommends that the government issue a life sciences vision akin to the one issued by the U.K. in 2021 to make the country more competitive to attract investment.
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DermR collection device

Dermr could displace skin biopsies with microneedle patch

Aug. 16, 2024
By Tamra Sami
Skin biopsies could be a thing of the past thanks to the development of a new non-invasive microneedle patch to pre-screen for skin cancer. Dermr Health Solutions Pty Ltd. founder and CEO Stefan Mazy told BioWorld that the fledgling genomics startup company is pushing the boundaries of science with its Dermr patch that quickly and painlessly extracts live skin cells in 15 seconds, drastically cutting the time and discomfort associated with traditional biopsy procedures.
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Wegovy available in Australia; hefty price likely to deter use

Aug. 15, 2024
By Tamra Sami
In the wake of shortages for Novo Nordisk A/S’ Ozempic (semaglutide), Australia’s Therapeutic Goods Administration has announced that Wegovy, which has the same active ingredient, is now available in Australia and is advising prescribers to stop prescribing Ozempic off-label for weight loss.
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Red and white blood cells

Ascentage moves BCL-2 inhibitor into fourth phase III

Aug. 14, 2024
By Tamra Sami
China’s National Medical Products Administration cleared Ascentage Pharma Group Corp. Ltd. to begin a registrational phase III trial of its BCL-2 selective inhibitor lisaftoclax (APG-2575) in combination with azacitidine for first-line treatment of newly diagnosed patients with higher-risk myelodysplastic syndrome.
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Thyroid anatomy

Visen’s palopegteriparatide hits endpoints in hypoparathyroidism

Aug. 13, 2024
By Tamra Sami
Visen Pharmaceuticals Co. Ltd.’s palopegteriparatide met both primary and secondary endpoints in the phase III Pathway trial conducted in China in adults with chronic hypoparathyroidism, according to top-line data. In the 26-week randomized, double-blind, placebo-controlled Pathway trial, 77.6% of patients treated with palopegteriparatide achieved the primary multicomponent endpoint compared to 0% for placebo.
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Girl in wheelchair

Neuren’s NNV-2591 positive in Angelman syndrome phase II trial

Aug. 13, 2024
By Tamra Sami
Neuren Pharmaceuticals Ltd.’s NNZ-2591 met the primary endpoints in a phase II trial in children with Angelman syndrome, with improvements seen in clinically important aspects of the disease, including communication, behavior, cognition and motor abilities, Neuren CEO Jon Pilcher said during an Aug. 9 conference call.
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Antibodies and red blood cells

MSD acquires Curon’s CD3 x CD19 bispecific antibody for up to $1.3B

Aug. 13, 2024
By Tamra Sami
Merck & Co. Inc. is acquiring Curon Biopharmaceutical Ltd.’s bispecific antibody CN-201 that targets CD3 and CD19 for B-cell associated diseases, for up to $1.3 billion. Under the terms of the deal, Merck (known as MSD outside of North America) through a subsidiary will acquire full global rights to CN-201 for an up-front payment of $700 million in cash. Curon is also eligible to receive up to $600 million in development and regulatory-based milestone payments. The deal is expected to close in the third quarter of 2024.
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Luye advances dual agonist for schizophrenia, Alzheimer’s

Aug. 13, 2024
By Tamra Sami
China’s National Medical Products Administration has cleared Luye Pharma Group Ltd.’s new schizophrenia candidate LY-03020 to enter phase I trials in China. Independently developed by Shanghai-based Luye, the new chemical entity is a dual agonist that targets both the trace amine-associated receptor 1 and the 5-HT2C receptor and is intended to treat schizophrenia and Alzheimer’s disease psychosis.
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Photo of jellyfish in aquarium lit by blue light
Aging

Jellyfish genes rejuvenate intestinal stem cells in fruit flies

Aug. 13, 2024
By Tamra Sami
Researchers in Japan were able to transfer genes from jellyfish into common fruit flies and discovered that the transferred gene suppressed an age-related intestinal issue in the flies. The findings suggest that studying genes specific to animals with high regenerative capability like jellyfish may uncover new mechanisms for rejuvenating stem cell function and extending the healthy lifespan of unrelated organisms.
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