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Home » Authors » Tamra Sami

Articles by Tamra Sami

Handshake behind digital globe

Everest licenses Asian rights to Kezar’s autoimmune drug zetomipzomib

Sep. 21, 2023
By Tamra Sami
Everest Medicines Ltd. is in-licensing Kezar Life Sciences Inc.’s phase II autoimmune disease candidate, zetomipzomib in a deal worth $132 million for greater China, South Korea and southeast Asia rights. Kezar’s lead molecule zetomipzomib (KZR-616) is a first-in-class, selective immunoproteasome inhibitor with broad therapeutic potential across multiple autoimmune diseases.
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3D peptide illustration

Peptidream, Genentech ink $1B deal for peptide-radioisotope drug conjugates

Sep. 20, 2023
By Tamra Sami
Peptidream Inc. and Genentech Inc., a Roche Holding company, signed a deal worth up to $1 billion to discover and develop macrocyclic peptide-radioisotope (peptide-RI) drug conjugates. Peptidream, of Kawasaki, Japan, will use its peptide discovery platform system technology to discover, optimize and develop macrocyclic peptide candidates for use as peptide-RI drug conjugates against targets of interest to Genentech. Genentech will pay Peptidream an up-front payment of $40 million and up to $1 billion in potential development, regulatory, and commercial-based milestones. In addition, Peptidream is eligible to receive tiered royalties on net sales (ex-Japan) of any products arising from the collaboration.
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Dendrimer illustration

Starpharma’s dendrimer platform delivers impressive results in bowel, ovarian cancer

Sep. 19, 2023
By Tamra Sami
Starpharma Holdings Ltd.'s nanoscale drug delivery technology shows enhanced safety and durable responses in phase II trials compared to standard of care therapies in patients with advanced colorectal and ovarian cancer.
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Innovent to raise $306M to advance late-stage pipeline

Sep. 14, 2023
By Tamra Sami
Innovent Biologics Inc. announced a HKD$2.37 billion (US$306 million) placement on the Hong Kong Stock Exchange (HKEX) to advance its late-stage pipeline, including mazdutide, a GLP-1R/GCGR dual agonist for diabetes and obesity. The company plans to offer 68 million new shares priced at HKD$34.92, which represents an 8.8% discount to the previous closing price of HKD$38.30 per share, the company said in a filing on the HKEX. Morgan Stanley is the sole placing agent.
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AWAK device in carry bag

Awak raises $20M series B to take portable kidney dialysis device to pivotal trials

Sep. 14, 2023
By Tamra Sami
Awak Technologies Pte Ltd. raised more than $20 million in a series B round that will position the company to potentially transform the management of chronic kidney disease with its wearable and portable peritoneal dialysis (PD) device designed to enable patients with end-stage kidney disease to have dialysis on the go.
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Global handshake silhouette

Hasten licenses Lib’s PCSK9 inhibitor for China rights in $325M deal

Sep. 13, 2023
By Tamra Sami
Hasten Biopharmaceutical Co. Ltd. has licensed greater China rights to Lib Therapeutics Inc.’s next-generation PCSK9 inhibitor lerodalcibep in a deal worth up to $325 million.
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IPO stock market ticker

Following Hong Kong IPO, Immuneonco looks to be rising star

Sep. 12, 2023
By Tamra Sami
After raising HKD$320 million (US$40.8 million) in its IPO on the Hong Kong Stock Exchange last week, Immuneonco Biopharmaceuticals Co. Ltd.’s stock has continued to rise, and analysts are expecting the Hong Kong market to pick up after a slack start to the year.
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Lung cancer illustration

Daiichi Sankyo’s HER3 ADC shows promise in EGFR-mutated advanced NSCLC

Sep. 11, 2023
By Tamra Sami
Daiichi Sankyo Co Ltd.’s HER3-directed antibody-drug conjugate patritumab deruxtecan showed clinically meaningful and durable responses in patients with EGFR-mutated locally advanced or metastatic non-small-cell lung cancer (NSCLC) in the Herthena-Lung1 phase II trial.
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Syringe and ampoules

Interim results show Brii’s therapeutic HBV vaccine induces immune response

Sep. 8, 2023
By Tamra Sami
Brii Biosciences Ltd.’s therapeutic vaccine for hepatitis B (HBV), BRII-179 (VBI-2601), induced functional immune responses – inducing broad antibody and T-cell responses – in patients with chronic HBV in a phase II trial that evaluated the vaccine in combination with pegylated interferon-alfa, according to interim results.
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China’s NMPA approves Gloria Bio’s zimberelimab as first PD-1 MAb for cervical cancer

Sep. 7, 2023
By Tamra Sami
China’s National Medical Products Administration (NMPA) has given the green light to Gloria Biosciences Co. Ltd.’s anti-PD-1 monoclonal antibody, zimberelimab (Yutuo, GLS-010), for treating second-line cervical cancer, making it the first immune checkpoint inhibitor approved in China for treating the disease.
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