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Home » Authors » Tamra Sami

Articles by Tamra Sami

Globe showing Asia-Pacific region

Top Trends of 2022: Asia Pacific shakes off pandemic isolation, but focus remains on sovereign supply chains, regional deals

Dec. 29, 2022
By Tamra Sami
Investment in the fourth quarter of 2022 was dismal in Asia Pacific, as the global venture community focused on preserving capital. And the region faced other challenges throughout the year, as leaders in Australia and across Asia became acutely aware of the vulnerabilities in their supply chains. But the year also saw some big deals and collaborations involving companies across Asia Pacific, along with advances in regenerative and digital medicine.
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Japan gears up for another round of drug price revisions but stakeholders push back

Dec. 29, 2022
By Tamra Sami
Japan’s Central Social Insurance Medical Council said it would issue similar drug price revisions in 2023 as it did in 2022 for drugs listed on the National Health Insurance, confirming the move to annual price cuts on drugs.
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Map of Australia with pills, vials and syringe

Australia delivers new National Medicines Policy aiming to deliver greater access to medicines

Dec. 28, 2022
By Tamra Sami
The Australian government delivered an early Christmas present to the biopharma industry in the form of a new National Medicines Policy giving voice to major industry goals – among them a clear vision to “achieve the world’s best health, social and economic outcomes for all Australians through a highly supportive medicines policy environment.”
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Peanut allergy

Aravax raises $20M series B round to take peanut allergy immunotherapy to phase II

Dec. 27, 2022
By Tamra Sami
With $20 million raised in a series B round led by Brandon Capital and Tenmile, Aravax Pty Ltd. is poised to begin phase II trials of its immunotherapy, PVX-108, for peanut allergy.
Read More
Concept of business partnership

Legochem out-licenses ADC targets to Amgen in ₩1.6 trillion deal

Dec. 27, 2022
By Tamra Sami
South Korea’s Legochem Bioscience Inc. inked a licensing deal with Amgen Inc. on Dec. 23 for five undisclosed antibody drug conjugate (ADC) targets worth up to ₩1.6 trillion (US$1.24 billion). Under the terms of the deal, Legochem will out-license global rights to Amgen for five undisclosed ADC targets and will receive an undisclosed up-front payment as well as development milestones and sales royalties. The companies did not disclose additional details.
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Cytomegalovirus in a human cell

Takeda’s maribavir bested by valganciclovir in post-transplant CMV study

Dec. 27, 2022
By Tamra Sami
Takeda Pharmaceutical Co. Ltd.'s oral antiviral, maribavir, failed to meet the primary endpoint of noninferiority compared to Roche Holding AG’s valganciclovir in the phase III Aurora study for cytomegalovirus (CMV) infection in hematopoietic stem cell transplant recipients. The multicenter, randomized, double-blind, double-dummy, active-controlled study was to form the basis for a future label expansion for the therapy.
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Cardiovascular

Reprogramming cardiac fibroblasts reverses cardiac fibrosis in mouse model

Dec. 23, 2022
By Tamra Sami
Researchers in Japan may have found a way to repair cardiac damage in patients suffering from chronic heart attack and heart failure by reprogramming cardiac fibroblasts (CFs) to cardiomyocytes (CMs) in a mouse model of chronic myocardial infarction (MI). Published online Dec. 12, 2022, in Circulation, the study showed that by tweaking the expression of a few key genes, researchers could reverse the lasting damage caused by heart attacks.
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Cytomegalovirus in a human cell

Takeda’s maribavir bested by valganciclovir in post-transplant CMV study

Dec. 22, 2022
By Tamra Sami
Takeda Pharmaceutical Co. Ltd.'s oral antiviral, maribavir, failed to meet the primary endpoint of noninferiority compared to Roche Holding AG’s valganciclovir in the phase III Aurora study for cytomegalovirus (CMV) infection in hematopoietic stem cell transplant recipients. The multicenter, randomized, double-blind, double-dummy, active-controlled study was to form the basis for a future label expansion for the therapy.
Read More
Peanut allergy

Aravax raises $20M series B round to take peanut allergy immunotherapy to phase II

Dec. 21, 2022
By Tamra Sami
With $20 million raised in a series B round led by Brandon Capital and Tenmile, Aravax Pty Ltd. is poised to begin phase II trials of its immunotherapy, PVX-108, for peanut allergy. “Our product is unlike other approaches that are in later stages of development, and those products generally use natural extracts from peanuts to treat peanut allergy,” Aravax CEO Pascal Hickey told BioWorld.
Read More
Chinese flag, pills

LG Chem Life Sciences out-licenses gout treatment to Innovent in $95M China deal

Dec. 20, 2022
By Tamra Sami
Innovent Biologics Inc. has in-licensed LG Chem Ltd.’s tigulixostat (LC-350189), a late-stage non-purine xanthine oxidase inhibitor for managing chronic hyperuricemia in patients with gout, in a deal worth up to $95 million.
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