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Home » Authors » Richard Staines

Articles by Richard Staines

Hal Barron.png

What next for GSK as R&D guru Hal Barron heads for the exit?

Jan. 20, 2022
By Richard Staines
When Glaxosmithkline plc’s new CEO, Emma Walmsley, was hiring a “dream team” of executives to lead the company in 2017, former Genentech whizz Hal Barron was the star signing as chief scientific officer. Lured away from Alphabet Inc.’s biotech subsidiary, Calico LLC, by a bumper pay deal, Barron was arguably Walmsley’s most important appointment. Walmsley badly needed a strong leader with credible expertise in science to lead the company’s R&D efforts, as her expertise and experience came from the company’s consumer operation. But as GSK plans to split later this year, Barron is heading for the exit to become CEO of California’s ambitious and enormously well-funded startup Altos Labs Inc.
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Acquisition target

UCB offers $1.9B for Zogenix and its rare epilepsy drug Fintepla

Jan. 19, 2022
By Richard Staines
UCB SA has unveiled plans to acquire Zogenix Inc. in a deal worth up to $1.9 billion (€1.7 billion), adding to its portfolio an approved drug aimed at rare forms of epilepsy. Brussels-based UCB will pay $26 per share in cash for the Emeryville, Calif.-based biotech, plus a contingent value right of $2 per share, which would pay out upon approval of the oral drug Fintepla (fenfluramine) for Lennox-Gastaut syndrome.
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Parkinson's disease illustration showing neurons containing alpha-synuclein

Sanofi in-licenses ABL Bio Parkinson’s drug for $1B as alpha-synuclein research heats up

Jan. 18, 2022
By Richard Staines
Targeting the toxic alpha-synuclein protein found in the brains of people with Parkinson’s is one of the most promising approaches to treat the disease in the clinic – but getting any drug into the brain is a challenge. Sanofi SA has joined with ABL Bio Inc. to solve this problem, in-licensing ABL-301, a preclinical bispecific antibody that locks on to misfolded alpha-synuclein but also includes a molecular “shuttle” that allows it to penetrate the blood-brain barrier.
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Patrick Doyle, CEO, Kbio Holdings Ltd.
Newco news

BAT follows tobacco rival Philip Morris into biotech, promising faster R&D with Kbio’s plant-based tech

Jan. 14, 2022
By Richard Staines
Following Philip Morris International Inc.’s controversial takeover of respiratory drug firm Vectura plc, British American Tobacco plc (BAT) is also making inroads into medical research with U.K.-based Kbio Holdings Ltd., a biotech focused on plant-based medicine.
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Pill in immersive interface

AZ delves further into AI, signing deals with Scorpion, Benevolentai

Jan. 13, 2022
By Richard Staines
Astrazeneca plc has announced two significant R&D deals with Scorpion Therapeutics Inc. and Benevolentai Ltd., which it hopes will sharpen its research into cancer, lupus and heart failure. Both of the deals involve artificial intelligence (AI) as a way to increase the probability of success during the clinical development process and reduce the chances of costly trial failures.
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Parkinson's disease illustration showing neurons containing alpha-synuclein

Sanofi in-licenses ABL Bio Parkinson’s drug for $1B as alpha-synuclein research heats up

Jan. 12, 2022
By Richard Staines
Targeting the toxic alpha-synuclein protein found in the brains of people with Parkinson’s is one of the most promising approaches to treat the disease in the clinic – but getting any drug into the brain is a challenge. Sanofi SA has joined with ABL Bio Inc. to solve this problem, in-licensing ABL-301, a preclinical bispecific antibody that locks on to misfolded alpha-synuclein but also includes a molecular “shuttle” that allows it to penetrate the blood-brain barrier.
Read More
Insomnia illustration

Idorsia gains first ever FDA approval for insomnia drug Quviviq

Jan. 10, 2022
By Richard Staines
After 25 years of research. Allschwil, Switzerland’s Idorsia Ltd. has had its first drug approved by the FDA – Quviviq (daridorexant) for adults with insomnia. The okay for Quviviq is the result of painstaking research led by the firm’s chief scientific officer, Martine Clozel, whose husband Jean-Paul Clozel is CEO.
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AZ’s Alexion buys rights to rare heart disease drug from Aduhelm discoverer Neurimmune for $760M

Jan. 7, 2022
By Richard Staines
Astrazeneca plc’s recently acquired Alexion Pharmaceuticals Inc. has signed a deal worth up to $760 million with Neurimmune AG, the Swiss biotech that discovered Alzheimer’s drug Aduhelm (aducanumab), buying rights to amyloidosis drug NI-006. While Biogen Inc.’s Aduhelm targets amyloid plaques thought to cause Alzheimer’s in the brain, the phase Ib drug in Alexion’s deal is intended to tackle the build-up of the rogue protein that causes heart disease caused by transthyretin amyloid cardiomyopathy (ATTR-CM).
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Antabio joins French consortium to tackle antibiotic resistance, as US mulls new funding model

Jan. 6, 2022
By Richard Staines
It’s been seven years since economist Jim O’Neill began his review on antimicrobial resistance, commissioned by the U.K. government to find ways to encourage development of badly needed new antibiotics. Since then, the pandemic has produced radical changes in society and forced pharma to refocus its R&D priorities at short notice. But COVID-19 has also raised awareness about the devastating effect that rogue pathogens can pose to society, and there are now serious moves to prevent a global catastrophe caused by antibiotic resistant bacteria.
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Connecting puzzle pieces

Amneal buys Saol’s baclofen portfolio in $83.5M deal

Jan. 5, 2022
By Richard Staines
Amneal Pharmaceuticals Inc. has bought a small portfolio of drugs from fellow U.S. biotech Saol Therapeutics Inc., adding the skeletal muscle relaxant baclofen to its portfolio and boosting its pipeline with a potential therapy to treat spasticity in a deal worth $83.5 million plus royalties.
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