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Home » Authors » Richard Staines

Articles by Richard Staines

Skin irritation on hands

Lilly’s $1.1B Dermira buy looks like good business as phase III eczema trials hit targets

Aug. 16, 2021
By Richard Staines
Eli Lilly and Co.’s $1.1 billion acquisition of Dermira Inc. early last year is looking like a smart move after the company’s atopic dermatitis (AD) drug, lebrikizumab, hit all its targets in two phase III trials. Lebrikizumab is an interleukin-13 antagonist and is part of Lilly’s strategy to build a dermatology portfolio to compete in a market dominated by Sanofi SA and Regeneron Pharmaceutical Inc.’s Dupixent (dupilumab), which was the first injected antibody drug available for AD in 2017. Lilly picked up Dermira, of Menlo Park, Calif., along with lebrikizumab in January last year shortly after the FDA granted lebrikizumab fast track status, paving the way for a potential six-month review.
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Vectura accepts £1.1B bid from tobacco giant Philip Morris

Aug. 13, 2021
By Richard Staines
Inhaled drugs developer Vectura Group plc has accepted a takeover bid from tobacco firm Philip Morris International Inc. (PMI), a move that has sparked revulsion from health campaigners but has been supported by investors. Shares in both firms ticked up in trading on Aug. 13 after Chippenham, U.K.-based Vectura accepted a bid worth around £1.1 billion (US$1.5 billion), rejecting a rival bid from U.S.-based private equity firm Carlyle Group.
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HIV infected cell
Newco news

Could HIV be cured by tackling ‘bumpy’ CD4 cells? France’s Diaccurate wants to find out

Aug. 12, 2021
By Richard Staines
Finding a functional cure to HIV is one of the biggest challenges in modern medicine, a task made so much tougher because of the virus’s ability to incorporate itself permanently into a host’s genome. But Diaccurate SAB, of Paris, thinks it may have a solution – and it’s all down to a discovery showing that the virus seems to make crucial immune CD4 cells go “bumpy”, lose their function and die.
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Businesswoman pressing dollar sign on touchscreen

Gentibio raises $157M in series A, targeting type 1 diabetes with its Tregs

Aug. 11, 2021
By Richard Staines
Gentibio Inc. has raised $157 million to develop its engineered regulatory T cells (Tregs), setting itself a target to cure type 1 diabetes and treat other diseases caused by the immune system. Boston-based Gentibio launched in August last year with $20 million seed funding from Orbimed, Novartis Venture Fund and RA Capital. Those investors stayed on into the next round, which was led by Matrix Capital Management with participation by Avidity Partners and JDRF T1D Fund.
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AZ, Daiichi Sankyo take aim at Roche as Enhertu beats Kadcyla in breast cancer trial

Aug. 10, 2021
By Richard Staines
Astrazeneca plc and Daiichi Sankyo Co. Ltd. are pushing forward with a challenge to Roche Holding AG with breast cancer drug Enhertu (trastuzumab deruxtecan) after it demonstrated superiority over the Swiss firm’s Kadcyla (trastuzumab emtansine) in a head-to-head trial.
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Philip Morris buys Otitopic and its cardiology inhaler as bidding war for Vectura heats up

Aug. 9, 2021
By Richard Staines
Tobacco firm Philip Morris International Inc. has announced another acquisition as it adopts a “beyond nicotine” strategy, snapping up Otitopic Inc., of Los Angeles, for an undisclosed sum.
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AZ, Daiichi Sankyo take aim at Roche as Enhertu beats Kadcyla in breast cancer trial

Aug. 9, 2021
By Richard Staines
Astrazeneca plc and Daiichi Sankyo Co. Ltd. are pushing forward with a challenge to Roche Holding AG with breast cancer drug Enhertu (trastuzumab deruxtecan) after it demonstrated superiority over the Swiss firm’s Kadcyla (trastuzumab emtansine) in a head-to-head trial.
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Questions over Morphosys’ $1.7B BET deal as Sierra snaps up AZ’s rival for $8M

Aug. 6, 2021
By Richard Staines
Sierra Oncology Inc. has swooped in on an early stage BET inhibitor from Astrazeneca plc, paying just $8 million up front for the myelofibrosis drug – a price that raises questions about the $1.7 billion Morphosys AG stumped up to buy Constellation Pharmaceuticals and its class rival.
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UK competition watchdog accuses Pfizer of illegal pricing of epilepsy drug

Aug. 5, 2021
By Richard Staines
The U.K.’s Competition and Markets Authority (CMA) has accused Pfizer Inc., together with a smaller U.K. player, of illegally overcharging the National Health Service (NHS) for the anti-epilepsy drug branded Epanutin (phenytoin sodium) before it went off patent in 2012.
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U.K. flag and capsules

NICE announces first quick funding okay as it plays catch-up after COVID-19

Aug. 4, 2021
By Richard Staines
The U.K.’s National Institute for Health and Care Excellence (NICE) is playing catch-up after seeing its workflow disrupted by the COVID-19 pandemic and has made the first funding approval using a new fast track appraisal process.
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