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Home » Authors » Lee Landenberger

Lee Landenberger

Articles

ARTICLES

Person scratching arm

Skin deep: Lilly and Incyte find success in treating atopic dermatitis

Jan. 30, 2020
By Lee Landenberger
Eli Lilly and Co. and Incyte Corp. are working on atopic dermatitis (AD) from several angles and finding success. The most recent example is the positive top-line results from their collaborative phase III trial of baricitinib in treating adults with moderate to severe atopic dermatitis that show the oral selective JAK inhibitor met the study’s primary and secondary endpoints.
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Newco news

Cell therapy firm Agex looks west to expand into Japan

Jan. 29, 2020
By Lee Landenberger
In its first step into Japan, Agex Therapeutics Inc. accelerates its development of engineering hypoimmunogenic cells, universal cells that can be used on patients who didn’t generate the original cell and without the need to use immunosuppressants.
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Up arrow breaking through wall

Acceleron’s upbeat phase II testing sotatercept in PAH launches the stock

Jan. 28, 2020
By Lee Landenberger
As Acceleron Pharma Inc.’s phase II trial of sotatercept hit its primary endpoint and some key secondary endpoints in significantly reducing pulmonary vascular resistance, the stock (NASDAQ:XLRN) reacted accordingly, gaining 50% on Jan. 28. The stock ended the day at $79.39, up $26.52.
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Silhouette made of gears

Born again: Neurotrope back in the game with bryostatin-1 in Alzheimer’s

Jan. 22, 2020
By Lee Landenberger
It was a trifecta to remember for Neurotrope Inc. on Wednesday as the company cast revealing light on a seemingly failed clinical program involving its lead candidate, had the NIH offer a grant to create a phase II trial to explore the program’s strengths, and then found institutional investors and individuals to pony up an $18 million registered direct offering for the company’s securities. It was a re-examination of data that resurrected Neurotrope’s hopes for its lead candidate months after a confirmatory phase II of bryostatin-1 failed to outperform a placebo in people with moderately severe to severe Alzheimer’s disease (AD) in the absence of Namenda (memantine, Allergan plc), an NMDA receptor antagonist.
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Clene Nanomedicine’s phase II for ALS muscles ahead

Jan. 21, 2020
By Lee Landenberger
What’s new inevitably includes an element of the old. Clene Nanomedicine Inc., which just completed enrollment and dosed the first patient in its phase II trial in amyotrophic lateral sclerosis (ALS), literally contains an element of the old in its lead nanocatalytic therapy: gold.
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U.S. money

Iterum in a $52M private placement from investors

Jan. 17, 2020
By Lee Landenberger
Iterum Therapeutics plc found a lifeline in the securities purchase agreement it made with an investors group for a $51.9 million private placement. The company plans to use that money to develop sulopenem, a penem anti-infective compound with oral and I.V. formulations.
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Frazier Healthcare closes Life Sciences X with more than $617M

Jan. 16, 2020
By Lee Landenberger
Frazier Healthcare Partners closed Frazier Life Sciences X LP, the company’s third fund, by exceeding its target with more than $617 million in capital commitments in an oversubscribed fundraiser.
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Hand holding money plant
Newco news

Kyverna Therapeutics emerges with $25M series A and a $587M Gilead agreement

Jan. 15, 2020
By Lee Landenberger
Not only did newly emergent Kyverna Therapeutics Inc. burst out of the gate with a $25 million series A, but it enhanced its entrance with a deal from Gilead Sciences Inc., one of the company’s initial funders, potentially worth $587.5 million.
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Newco news

AI startup Zebiai inks new deals with Google and X-Chem

Jan. 14, 2020
By Lee Landenberger
When Zebiai Therapeutics Inc.’s CEO, Rick Wagner, went about naming his new machine learning company, he wanted it to connote something dramatic that displayed the company’s potential to reach into the seemingly boundless future technology had unlocked.
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Pfizer’s agreements with Biogen and Axsome lead day of deals

Jan. 13, 2020
By Lee Landenberger
Pfizer Inc. was a swinging door today as it sold its small molecule for treating patients with behavioral and neurological symptoms to Biogen Inc., while licensing reboxetine’s data and intellectual property and granting esreboxetine’s development and commercialization rights to Axsome Therapeutics Inc.
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View All Articles by Lee Landenberger

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