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Home » Authors » Lee Landenberger

Lee Landenberger

Articles

ARTICLES

Allena's shares plunge despite reloxaliase phase III hitting primary endpoint in EH study

Nov. 8, 2019
By Lee Landenberger
Allena Pharmaceuticals Inc.'s phase III URIROX-1 trial of reloxaliase hit its primary endpoint, with a statistically significant reduction in urinary oxalate (Uox) in patients with enteric hyperoxaluria (EH), while its phase II Study 206 trial showed reduced plasma oxalate reduction in patients with EH and advanced chronic kidney disease (CKD).
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ASH abstracts move the market

Nov. 7, 2019
By Lee Landenberger
Emerging from the tsunami of abstracts from the nearly here American Society of Hematology (ASH) annual meeting in Orlando, Fla., were data that sent some stocks upward on Wednesday. Most notably, Constellation Pharmaceuticals Inc. (NASDAQ:CNST) was a huge winner as its shares nearly doubled in value as they closed at $28,10, up $13.33, for a gain of 90.25%.
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Map of China

Beigene, Amgen ink $2.7B China deal

Nov. 6, 2019
By Lee Landenberger and Elise Mak
When the time was right to make a powerful Western biotech welcome in China, Beigene Ltd. was ready when Amgen Inc. came calling. Its massive $2.7 billion cash equity investment in Beigene buys Amgen an oncology footprint in China.
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Centering itself: Epicentrx launches a phase III in SCLC

Nov. 6, 2019
By Lee Landenberger
Corey Carter, whose company Epicentrx Inc. just dosed its first patient in a phase III trial for treating third-line and beyond small-cell lung cancer (SCLC), has made studying the disease a life goal. "With my military background, I noticed that smoking rates are higher there," Carter, the company's president and CEO, told BioWorld. "That's when it became important to me. Then, also, my dad had small-cell lung cancer."
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Amgen says it wants the Revolution for its phase Ib

Nov. 5, 2019
By Lee Landenberger
Amgen Inc. and Revolution Medicines Inc. will collaborate on a clinical trial evaluating the combination of RMC-4630, Revolution's SHP2 inhibitor, and Amgen's AMG-510, a KRAS-G12C inhibitor. Amgen will conduct the phase Ib trial to treat patients with advanced solid tumors harboring the KRAS G12C mutation and Revolution will provide Amgen with RMC-4630.
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Through Beigene, Amgen helps awaken the sleeping giant; $2.7B cash investment

Nov. 4, 2019
By Lee Landenberger and Elise Mak
When the time was right to make a powerful Western biotech welcome in China, Beigene Ltd. was ready when Amgen Inc. came calling. Its massive $2.7 billion cash equity investment in Beigene buys Amgen an oncology footprint in China.
Read More
Martin Jefson, CEO, Pinteon

Pinteon raises $17M series A, launches a phase I trial and starts prepping for series B

Nov. 1, 2019
By Lee Landenberger
With a $17 million series A fundraiser completed, Pinteon Therapeutics Inc., of Cambridge, Mass., is keeping its eyes on the phase I trial it started in September testing PNT-001, a tau antibody that targets cis-pT231 tau, a toxic epitope that drives neurodegenerative disease.
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Cyclerion reorganizes in wake of two phase II troubles forsGC stimulator praliciguat

Oct. 31, 2019
By Lee Landenberger
Two phase II stumbles for startup Cyclerion Therapeutics Inc., an Ironwood Pharmaceuticals Inc. spinout, crushed the stock (NADAQ:CYCN), which closed down a steep 79.5% on Wednesday.
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Brian MacDonald, founder and interim CEO, Disc Medicine

Express yourself: Disc raises $50M to research regulating hepcidin expression

Oct. 30, 2019
By Lee Landenberger
Brian MacDonald's pursuit of an approved hepcidin therapy at Merganser Biotech Inc. didn't quite pan out, but that didn't stop him from taking up Atlas Venture's offer to try it once again on a different tack.
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Eye chart

Iveric's positive top-line data for macular degeneration brings its stock into focus

Oct. 29, 2019
By Lee Landenberger
Upbeat top-line data for New York-based Iveric Bio Inc.'s phase IIb trial testing Zimura in dry age-related macular degeneration propelled the company stock (NASDAQ:ISEE) 82.8% upward in Monday's trading, a big success in a company that rebranded itself earlier this year.
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View All Articles by Lee Landenberger

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