Phase III results for evinacumab from Regeneron Pharmaceuticals Inc. released Wednesday show a 49% LDL cholesterol reduction in patients with homozygous familial hypercholesterolemia (HoFH) when compared to lipid-reducing therapies alone.
The multiple months that typically separate a successful round of fundraising and entering the clinic are being brushed aside by Landos Biopharma Inc. as the company races toward two phase II trials following its just completed $60 million series B financing.
A choppy year for Amgen Inc. may be smoothing out after the U.S. District Court of New Jersey ruled that patents for Sandoz Inc.'s biosimilar, Erelzi (etanercept-szzs), a potential competitor to Amgen's highly lucrative arthritis treatment Enbrel (etanercept), should never have been granted.
The advisory committee meeting (adcom) that slowed progress for Amarin Corp. and its pending supplemental new drug application (sNDA) for expanding the labeling of Vascepa (icosapent ethyl) was a shock not only to the company but to investors, too, as the stock (NASDAQ:AMRN) took a battering Friday.
A successful $55 million series D fundraising allowed Oric Pharmaceuticals Inc.'s CEO to lean upon on a truism that's often easily waved away in business fundamentals as he overhauled the company management.
With a $33 million series B round now under his belt, Glycomine Inc.'s CEO said serendipity is a large part of what brought the company to study glycosylation disorders, a rare disease that affects about 1,000 people.
Neoleukin Therapeutics Inc. and Aquinox Pharmaceuticals Inc. agreed to a merger in which Aquinox acquires Neoleukin, and Neoleukin becomes the official company name. The combined company plans to develop and commercialize computationally designed protein therapeutics for unmet needs in immuno-oncology, inflammation and autoimmunity.
Aveo Oncology Inc. and Kyowa Kirin Co. Ltd. amended their 2006 license agreement so that Kyowa Kirin can buy back the non-oncology rights of tivozanib in Aveo territories, including the U.S. and the EU, while Aveo retains U.S. rights in cancer.
No day is a good one for a company connected to a failed phase III trial, but Monday's hammering of Glycomimetics Inc. (NASDAQ:GLYC) shares was particularly tough as the greater market's weakness provided no shelter.
Poor second-quarter sales of newly launched Inbrija, the first and only inhaled levodopa, pummeled Acorda Therapeutics Inc. (NASDAQ:ACOR) as the stock lost nearly half its value, 48.9%, on Friday.
