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Home » Authors » Lee Landenberger

Lee Landenberger

Articles

ARTICLES

Sage’s phase III depression trial hits endpoints, but misses mark for some investors

Feb. 16, 2022
By Lee Landenberger
A phase III study of Sage Therapeutics Inc.’s zuranolone in major depressive disorder hit not only its primary endpoint but also its key secondary endpoint. Despite that, the Cambridge, Mass.-based company’s share value (NASDAQ:SAGE) closed 17.4% lower Feb. 16, at $35.91 each.
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COVID-19 research illustration

Worldwide, there’s a long line of long COVID studies

Feb. 15, 2022
By Lee Landenberger
More than 100 million people worldwide are thought to have post-acute COVID-19 syndrome, roughly 40% of everyone on the planet who’s had COVID. Now, thousands of them are beginning to cycle through clinical and preclinical studies designed to get a better look at this little understood aspect of the pandemic.
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Cancer cell, dropper, test tubes

Reunited: Immunogen joins a $1.74B deal with Lilly in cancer

Feb. 15, 2022
By Lee Landenberger
Immunogen Inc. and Eli Lilly and Co., having already seen a collaboration collapse in 2018, will try it again. Immunogen granted the exclusive rights to research, develop and commercialize antibody-drug conjugates (ADCs) that are directed toward targets Lilly will select. Waltham, Mass.-based Immunogen will receive $13 million up front from Lilly and is eligible to receive another $32.5 million in exercise fees if Lilly licenses all the targets. Down the road, Immunogen could receive as much as $1.7 billion in exercise fees and milestones payments.
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Stock merger illustration

Collegium buys Biodelivery Sciences for $604M

Feb. 14, 2022
By Lee Landenberger
Collegium Pharmaceutical Inc. said it plans to acquire all outstanding shares of Biodelivery Sciences International Inc. for $5.60 each, putting the price tag at about $604 million. At the heart of the deal are Biodelivery Sciences' Belbuca (buprenorphine buccal film), a schedule III opioid, and Elyxyb (celecoxib), an oral migraine treatment that gives Collegium a foothold into the neurology market.
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Optogenetics illustration

Proqr stock staggers as phase II/III study in rare genetic disease misses

Feb. 11, 2022
By Lee Landenberger
Proqr Therapeutics NV stock lost three-quarters of its value as word got out that its pivotal phase II/III study of sepofarsen in treating a tough, rare and genetic retinal disease failed to hit the primary endpoint. CEO Daniel de Boer said he was “shocked by the unexpected outcome” based on data from earlier studies. He added that he is unsure if Proqr will continue developing its therapy for treating CEP290-mediated Leber congenital amaurosis 10 until it understands the new results.
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3D dollar sign

Curevo raises a $60M series A to tackle a blockbuster

Feb. 10, 2022
By Lee Landenberger
Curevo Vaccine Inc. closed on a $60 million series A financing designed to take the company through releasing top-line data for its phase IIb study of CRV-101 for treating shingles in older adults. That means taking on a blockbuster, Shingrix from Glaxosmithkline plc.
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With $140M series C, Ventus ‘Resolves’ to advance discovery platform, multiple programs

Feb. 9, 2022
By Lee Landenberger
Ventus Therapeutics Inc. closed a $140 million series C financing to continue scaling its platform to address previously undruggable targets. The company said it plans to advance programs targeting key modulators of the innate immune system and other therapies, including two targeting NLRP3 (NLR pyrin domain-containing 3) and one targeting cGAS, into the clinic. It plans to submit INDs for three programs in 2023.
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Worldwide, there’s a long line of long COVID studies

Feb. 9, 2022
By Lee Landenberger
More than 100 million people worldwide are thought to have post-acute COVID-19 syndrome, roughly 40% of everyone on the planet who’s had COVID. Now, thousands of them are beginning to cycle through clinical and preclinical studies designed to get a better look at this little understood aspect of the pandemic.
Read More
Clarissa Desjardins, founder and CEO, Congruence

Congruence raises a $50M series A to develop rare disease therapies

Feb. 8, 2022
By Lee Landenberger
Congruence Therapeutics Inc. has closed on a $50 million series A financing to design small molecules to treat rare diseases with protein misfolding. Montreal-based Congruence uses structural bioinformatics, computational chemistry and machine learning in its in silico platform that detects key biophysical features on proteins. That data are used to then design drugs.
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Moderna COVID-19 vaccine

‘Not complicated’: ACIP unanimously recommends Moderna’s COVID-19 vaccine to the CDC

Feb. 4, 2022
By Lee Landenberger
The CDC’s Advisory Committee on Immunization Practices (ACIP) has unanimously recommended the agency endorse administering Moderna Inc.'s COVID-19 vaccine, Spikevax (elasomeran), to adults. The vote was a strong echo of the FDA’s full approval of the vaccine for adults only a few days earlier, on Jan. 31. After hearing safety and efficacy data from Moderna and an internal analysis of that data from the CDC, ACIP recommended by a vote of 13-0 that the CDC endorse the vaccine’s use for people 18 years and older.
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View All Articles by Lee Landenberger

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