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Home » Keywords » Treg

Items Tagged with 'Treg'

ARTICLES

Colorized scanning electron microscope image of regulatory T cells and antigen-presenting cells.
Newco news

Japan’s Regcell launches in US with $45.8M to advance Treg platform

March 18, 2025
By Tamra Sami
Japanese-founded Regcell Inc. has raised $45.8 million and is redomiciling to the U.S. to accelerate clinical development of its pioneering regulatory T-cell (Treg) platform for autoimmune diseases and transplantation.
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Biotech deal illustration

Quell’s Treg approach lands $2B Astrazeneca deal to focus on IBD, type 1 diabetes

June 19, 2023
By Nuala Moran
Regulatory T-cell specialist Quell Therapeutics Ltd. has sealed a potential $2 billion agreement under which Astrazeneca plc is taking rights to two autologous Treg cell therapies for treating inflammatory bowel disease (IBD) and type 1 diabetes. Quell will receive $85 million up front, the majority of which is in cash, with a modest (undisclosed) equity investment. Reaching the $2 billion headline figure will involve a series of development and commercial milestones and royalties on sales.
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Gold chain link engraved with "partnership"

Trexbio strengthens Lilly connection in $1.1B deal; Kronos, Selecta, 3T join dealmaking party

Jan. 9, 2023
By Jennifer Boggs
Trex Bio Inc., which kicked off 2022 with a big pharma partnership, is back at it again, starting the new year with a potential $1.1 billion agreement with original backer Eli Lilly and Co. targeting immune-mediated diseases. Under the terms, Trexbio gets $55 million up front, with Lilly picking up an exclusive worldwide license for candidates from three programs.
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Hand holding dollar sign

Quell’s Treg cell therapy heading to clinic with $156M series B

Nov. 30, 2021
By Nuala Moran

LONDON – Quell Therapeutics Ltd. has raised $156 million in an oversubscribed series B, enabling it to start a phase I/II trial of its engineered T regulatory (Treg) cell therapy for promoting long-term immune tolerance in liver transplant patients, averting the need for chronic immunosuppression.


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Gold wireframe handshake

Rapid returns for shareholders as Pandion agrees to $1.85B Merck buyout

Feb. 25, 2021
By Cormac Sheridan
Merck & Co. Inc. is paying $1.85 billion, or $60 per share, to acquire Pandion Therapeutics Inc. on the back of early stage data in human volunteers for its lead program, PT-101, an engineered interleukin-2 mutein fused to an Fc backbone, which is designed to stimulate targeted expansion of regulatory T cells for use in autoimmune disease indications.
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Treg cells

Another startup, another planet: Alderaan closes $21M A round for anti-CD25 antibodies

Jan. 9, 2020
By Cormac Sheridan
Alderaan Biotechnology SAS is the latest contender to enter the hotly contested world of regulatory T-cell (Treg) depletion in cancer.
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