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Home » Keywords » antibiotics

Items Tagged with 'antibiotics'

ARTICLES

Petri dish and capsules
Infection

DCB-001, first-in-class specific antibiotic against multidrug-resistant strains

March 3, 2025
Dimicare Biotech and affiliated organizations have presented the discovery and preclinical characterization of DCB-001, a trichloroacetimidamide compound being developed as a novel precision antibiotic against multidrug-resistant strains.
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Bacteria in petri dishes
Infection

Discovery of new antibiotic compounds against multidrug-resistant gram-positive pathogens

Feb. 17, 2025
Researchers from Shanxi Medical University, Nanjing Agricultural University and China Pharmaceutical University, have detailed the discovery and preclinical characterization of antibiotic candidates against multidrug-resistant gram-positive pathogens.
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Bacterial colonies in petri dishes
Infection

Gates Foundation, Novo Nordisk Foundation and Wellcome set sights on antimicrobial resistance

Feb. 13, 2025
The Gates Foundation, Novo Nordisk Foundation and Wellcome have announced the launch of the Gram-Negative Antibiotic Discovery Innovator (Gr-ADI), a $50 million investment that will focus on combatting antimicrobial resistance (AMR) caused by a specific range of bacteria that are among the leading contributors to AMR-associated deaths.
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Petri dishes

New drugs with the same old resistance tricks?

Jan. 21, 2025
By Coia Dulsat
According to the World Health Organization (WHO), multidrug-resistant pathogens caused over 1.27 million deaths worldwide in 2020. And figures are rising, with projections pointing to antimicrobial resistance surpassing cancer as the leading cause of death by 2050. Now, researchers at the HUN-REN Biological Research Center have unveiled the role of pre-existing genetic variabilities and specific cross-resistance patterns among several antibiotics designed to combat gram-positive bacteria.
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Lungs wireframe illustration
Infection

Glox awarded funding to advance antibiotics for antimicrobial-resistant lung infections in cystic fibrosis

Jan. 21, 2025
Glox Therapeutics Ltd. has been awarded a share of a £3 million (US$3.7 million) collaborative discovery program launched by the Cystic Fibrosis Antimicrobial Resistance (CF AMR) syndicate. The syndicate is a cross-sector initiative driven by Medicines Discovery Catapult, Lifearc and Cystic Fibrosis Trust.
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Drug discovery illustration
Infection

CARB-X grant supports Justus Liebig University Giessen to develop BamA inhibitors for gram-negative pathogens

Jan. 17, 2025
Combating Antibiotic-Resistant Bacteria Biopharmaceutical Accelerator (CARB-X) will award a seed grant of $610,000 to Justus Liebig University Giessen (JLU) to support the definition of a lead optimization path for the development of a direct-acting peptide therapeutic based on a natural-product scaffold targeting gram-negative pathogens.
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Petri dishes
Infection

New drugs with the same old resistance tricks?

Jan. 16, 2025
By Coia Dulsat
According to the World Health Organization (WHO), multidrug-resistant pathogens caused over 1.27 million deaths worldwide in 2020. And figures are rising, with projections pointing to antimicrobial resistance surpassing cancer as the leading cause of death by 2050. Now, researchers at the HUN-REN Biological Research Center have unveiled the role of pre-existing genetic variabilities and specific cross-resistance patterns among several antibiotics designed to combat gram-positive bacteria.
Read More
Futuristic medicine research illustration with petri dishes and pipette
Infection

CARB-X grant supports progression of Basilea’s LptA inhibitor

Dec. 23, 2024
Basilea Pharmaceutica Ltd. has been awarded an additional $7.3 million from CARB-X (Combating Antibiotic-Resistant Bacteria Biopharmaceutical Accelerator) to support the progression of the company’s novel antibiotic candidate, BAL-2420.
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Colorized scanning electron micrograph of MRSA.
Infection

New MetRS inhibitor shows in vitro and in vivo activity against relevant gram-positive pathogens

Nov. 29, 2024
Researchers from the University of Washington are developing new antibiotics targeting bacterial methionyl-tRNA synthetase (MetRS). This enzyme is responsible for charging tRNA(met) with methionine and integral to protein synthesis.
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Digital lungs illustration
Infection

Bioversys joins RespiriNTM program to advance efforts for NTM pulmonary disease

Oct. 22, 2024
Bioversys AG has joined the EU-funded RespiriNTM program that is exploring multiple approaches to determine new targets for antimycobacterial compounds, define and optimize novel inhibitors and advance these through the process of hit-to-lead up until first-in-human trials.
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More Articles Tagged with 'antibiotics'

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