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Home » Keywords » Harvard University

Items Tagged with 'Harvard University'

ARTICLES

3D illustration of blood cells, plasmodium causing malaria illness
Infection

Plasmodium essential gene map gives malaria pharmacologic clues

Feb. 13, 2025
By Mar de Miguel
Two simultaneous but independent studies published in Science identified, by introducing mutants into its genome, the essential and nonessential genes of Plasmodium knowlesi, one of the malaria parasites related to the dreaded Plasmodium vivax. Their results could help in the development and prioritization of antimalarial strategies.
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Video still showing the brain inside an adult fruit fly

The map for a journey to the center of the brain

Dec. 27, 2024
By Mar de Miguel
In the 1970s, scientists from several countries proposed to reconstruct, one by one, all the neurons in the brain as they appear under an electron microscope. They started with a small worm. Caenorhabditis elegans has only 302 neurons. It took 16 years. How much time would be required to repeat this arduous task for the 100 billion neurons in the human brain?
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Video still showing the brain inside an adult fruit fly

The map for a journey to the center of the brain

Dec. 24, 2024
By Mar de Miguel
In the 1970s, scientists from several countries proposed to reconstruct, one by one, all the neurons in the brain as they appear under an electron microscope. They started with a small worm. Caenorhabditis elegans has only 302 neurons. It took 16 years. How much time would be required to repeat this arduous task for the 100 billion neurons in the human brain?
Read More
Video still showing the brain inside an adult fruit fly
Neurology/psychiatric

The map for a journey to the center of the brain

Dec. 23, 2024
By Mar de Miguel
In the 1970s, scientists from several countries proposed to reconstruct, one by one, all the neurons in the brain as they appear under an electron microscope. They started with a small worm. Caenorhabditis elegans has only 302 neurons. It took 16 years. How much time would be required to repeat this arduous task for the 100 billion neurons in the human brain?
Read More
3D illustration of acute myeloid leukemia cells
Cancer

DEG-77 shows robust antiproliferative effect in AML and ovarian cancer models

Aug. 21, 2024
Both casein kinase 1α (CK1α) and zinc finger protein Helios (IKZF2) are among the targets most recently evaluated for the treatment of acute myeloid leukemia (AML). A growing number of molecules against these targets acting as degraders or inhibitors are actively being investigated.
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Photomicrograph of fine needle aspiration cytology of a pulmonary nodule showing adenocarcinoma, a type of non-small-cell carcinoma.
Immuno-oncology

Triple nanotherapy could benefit more lung cancer patients

June 20, 2024
By Mar de Miguel
A new approach against non-small-cell lung cancer (NSCLC) has combined immunotherapy with molecularly targeted therapy to activate the immune response and inhibit oncogenic pathways, which prevented tumor progression and eliminated cancer cells. Brigham and Women’s Hospital scientists have developed nanoparticles loaded with antibody conjugates that could deliver large amounts of treatment to the tumor tissue. This new strategy could improve the results of conventional immunotherapy in these patients and reduce toxicity of existing treatments.
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Excitatory (pyramidal) neurons colored by size.
Neurology/psychiatric

Full reconstruction of brain tissue block gives insights into structure, function

May 17, 2024
By Mar de Miguel
A group of scientists from Harvard University have observed and reconstructed the human brain at the resolution of the electron microscope, with all its cells, following all the connections between its neurons around a cubic millimeter of a tissue sample. They took 10 years and the data occupies 1.4 petabytes (1,400 terabytes). However, they are already planning a bigger project.
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Human anatomy
Immune

Enhancing organ preservation: SNC-80 slows metabolic activities, preserving cell and tissue viability

Feb. 27, 2024
Researchers recently conducted a study to identify small molecules slowing metabolism and mimicking states normally induced by hypothermia or hibernation. The final aim was the discovery of drugs to preserve living cells, tissues and organs ex vivo, and potentially in vivo.
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Ribosome as part of an biological cell constructing mRNA molecules
Infection

Ribosome-binding antibiotic cresomycin strikes against multidrug-resistant pathogens

Feb. 22, 2024
By Xavier Bofill Bruna
Researchers from the University of Illinois at Chicago and Harvard University have published details on the chemical synthesis and microbiological evaluation of a ribosome-binding antibiotic – cresomycin (CRM) – that was able to overcome antimicrobial resistance of major pathogenic bacteria including Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa and others.
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Petri dish and capsules
Infection

CARB-X funds research at Harvard on oral antibiotics for resistant bacteria

Feb. 14, 2024
Combating Antibiotic-Resistant Bacteria Biopharmaceutical Accelerator (CARB-X), led by Boston University, is awarding $1.2 million to the Andrew G. Myers Research Group at Harvard University to develop a series of enhanced oral antibiotics that directly target a range of antibiotic-resistant bacteria which cause serious lower respiratory tract and skin and soft tissue infections.
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More Articles Tagged with 'Harvard University'

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