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Home » Keywords » multiple sclerosis

Items Tagged with 'multiple sclerosis'

ARTICLES

Apimeds Pharmaceuticals raises $13.5M from NYSE American debut

May 20, 2025
By Marian (YoonJee) Chu
No Comments
Apimeds Pharmaceuticals US Inc. (APUS), a subsidiary of Kospi-listed Inscobee Inc., said May 12 that it raised $13.5 million from its stock sale on the NYSE American exchange May 9 through an offering of 3.375 million shares at $4 per share. Hopewell, N.J.-based APUS is the second pharmaceutical company with Asian ties to float shares on the U.S. market this year.
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Apimeds Pharmaceuticals raises $13.5M from NYSE American debut

May 14, 2025
By Marian (YoonJee) Chu
No Comments
Apimeds Pharmaceuticals US Inc. (APUS), a subsidiary of Kospi-listed Inscobee Inc., said May 12 that it raised $13.5 million from its stock sale on the NYSE American exchange May 9 through an offering of 3.375 million shares at $4 per share. Hopewell, N.J.-based APUS is the second pharmaceutical company with Asian ties to float shares on the U.S. market this year.
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Multiple sclerosis-damaged myelin
Neurology/psychiatric

AFC-5128 mitigates acute and chronic EAE via P2X7 receptor antagonism

April 29, 2025
Multiple sclerosis (MS) is characterized by persistent inflammation, primarily driven by CNS-resident immune cells like microglia, particularly in the progressive stages. The purinergic P2X7 receptor (P2X7R) is widely expressed on immune cells and is elevated on reactive astrocytes and microglia of MS lesions.
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Epstein-Barr virus 3D illustration
Immune

Genes and Epstein-Barr virus immune response increase MS risk

March 17, 2025
By Mar de Miguel
A combination of Epstein-Barr virus (EBV) antibodies and genetic factors may be linked to an increased risk of multiple sclerosis (MS), according to a study led by scientists at Karolinska Institutet and Stanford University. “The Epstein-Barr virus has been a suspect for many years for having a role in causing MS. The evidence for it has increased though one has not really reached complete proof of its role,” Tomas Olsson told BioWorld.
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Neurology/psychiatric

New EBP inhibitors disclosed in Biogen patent

March 14, 2025
Biogen Inc. has divulged 3-β-hydroxysteroid-δ(8),δ(7)-isomerase (EBP) inhibitors reported to be useful for the treatment of autoimmune disease and multiple sclerosis.
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Multiple sclerosis
Neurology/psychiatric

Grant supports evaluation of Myrobalan’s GPR17 antagonist for progressive MS

March 14, 2025
Myrobalan Therapeutics Inc. has been awarded a grant of over $850,000 from the National Multiple Sclerosis Society to support the preclinical and translational development of MRO-002, a G-protein-coupled receptor 17 (GPR17) antagonist, for the treatment of progressive multiple sclerosis (MS).
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Justin Rubio working in the lab
Inflammatory

Inflammation appears to cause mutations linked to MS progression

March 11, 2025
By Tamra Sami
For the first time, researchers have identified that inflammation – long associated with multiple sclerosis (MS) – appears to cause increased mutations that damage neurons linked to MS progression. Researchers at the Florey Institute and the University of Melbourne studied MS brain lesions, which are areas of past or ongoing brain inflammation that are visible as spots on MRI scans.
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Neurology/psychiatric

Biogen patents new GPR17 antagonists for multiple sclerosis

March 11, 2025
Biogen Inc. has disclosed uracil nucleotide/cysteinyl leukotriene receptor (GPR17; P2Y-Like) antagonists with improved brain penetration reported to be useful for the treatment of multiple sclerosis.
Read More
Justin Rubio working in the lab
Inflammatory

Inflammation appears to cause mutations linked to MS progression

March 10, 2025
By Tamra Sami
For the first time, researchers have identified that inflammation – long associated with multiple sclerosis (MS) – appears to cause increased mutations that damage neurons linked to MS progression. Researchers at the Florey Institute and the University of Melbourne studied MS brain lesions, which are areas of past or ongoing brain inflammation that are visible as spots on MRI scans.
Read More
Neurology/psychiatric

NEK2 inhibition improves neurological function in model of multiple sclerosis

March 7, 2025
Researchers from General Hospital of Tianjin Medical University presented data from a study that aimed to explore the role of NIMA-related kinase 2 (NEK2) in regulating B-cell immunity in autoimmune diseases. It was demonstrated that NEK2 is highly expressed in patients with multiple sclerosis.
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More Articles Tagged with 'multiple sclerosis'

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