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Home » Keywords » hepatitis B

Items Tagged with 'hepatitis B'

ARTICLES

Drug Farm harvests new immunomodulators with AI-gene editing tech

June 24, 2025
By Marian (YoonJee) Chu
No Comments
Shanghai Yao Yuan Biotechnology Ltd., also known as Drug Farm, is advancing a portfolio of immune-modulating therapies for various indications including hepatitis B virus, hepatocellular cancer and a relatively new rare genetic disease called ROSAH, an acronym for retinal dystrophy, optic nerve edema, splenomegaly, anhidrosis, and headache.
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AI-generated illustration of DNA double helix

Drug Farm harvests new immunomodulators with AI-gene editing tech

June 20, 2025
By Marian (YoonJee) Chu
No Comments
Shanghai Yao Yuan Biotechnology Ltd., also known as Drug Farm, is advancing a portfolio of immune-modulating therapies for various indications including hepatitis B virus, hepatocellular cancer and a relatively new rare genetic disease called ROSAH, an acronym for retinal dystrophy, optic nerve edema, splenomegaly, anhidrosis, and headache.
Read More
Infection

Japanese scientists divulge new isoindoline compounds for viral infections

May 29, 2025
The Institute of Physical and Chemical Research and Kyoto University have synthesized isoindoline compounds reported to be useful for the treatment of viral infections.
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Illustration of liver infection
Infection

ABI-4334 outperforms vebicorvir in HBV suppression

May 13, 2025
No Comments
Current therapies for chronic hepatitis B virus (HBV) infection can effectively suppress viral replication but do not achieve a functional or complete cure. Capsid assembly modulators inhibit the assembly of viral capsids, prevent the encapsidation of pregenomic RNA, and interfere with both the formation and amplification of covalently closed circular DNA, which is essential for viral persistence.
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3d rendering of bispecific antibodies
Infection

Cell-penetrating bispecific HBcAg/pre-S1 antibody suppresses HBV replication and secretion

April 1, 2025
Hepatitis B virus (HBV) infection is associated with liver diseases, including chronic hepatitis, which notably increases the risk of cirrhosis and hepatocellular carcinoma (HCC) development. Although some of the current treatment strategies promote virological suppression, they are insufficient to halt HCC development.
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Immuno-oncology

Aligos Therapeutics patents new inhibitors of PD-1, PD-L1 or PD-1/PD-L1 interaction

Feb. 4, 2025
Aligos Therapeutics Inc. has disclosed programmed cell death 1 (PDCD1; PD-1; CD279) and/or PD-1 ligand 1 (PD-L1; CD274) and/or PD-1/PD-L1 interaction inhibitors reported to be useful for the treatment of hepatocellular carcinoma and hepatitis B.
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Hepatitis B virus
Infection

SA-1211, a dual-target siRNA with promising antiviral activity in AAV-HBV mice

Dec. 4, 2024
Researchers from Suzhou Siran Biotech Co. Ltd. presented the discovery and preclinical characterization of SA-1211, an N-acetylgalactosamine (GalNAc)-conjugated siRNA dimer targeting both hepatitis B virus (HBV) and PD-L1 gene expression, being developed as a potential new therapeutic candidate for the treatment of chronic hepatitis B (CHB).
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Infection

Preclinical characterization of Tune-401, a first-in-class LNP-encapsulated epigenetic silencer therapy for hepatitis B

Dec. 4, 2024
Tune Therapeutics Inc. is evaluating Tune-401.
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Transmission electron micrograph of hepatitis B virus particles
Infection

Therapeutic hepatitis B vaccine generates robust HBc-specific T-cell responses in preclinical tests

Dec. 2, 2024
Researchers from presented preclinical data for AVX-70371, a novel therapeutic vaccine being developed for the treatment of chronic hepatitis B virus (HBV) infection.
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Infection

EDP-514 demonstrates favorable preclinical PK profile, excellent target tissue penetration

Nov. 22, 2024
Enanta Pharmaceuticals Inc. has released preclinical pharmacokinetics (PK) data for EDP-514, a potent and selective class II core assembly modulator in phase I development for the oral treatment of hepatitis B.
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More Articles Tagged with 'hepatitis B'

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