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Home » Keywords » hidradenitis suppurativa

Items Tagged with 'hidradenitis suppurativa'

ARTICLES

Street less than JAK’d about Incyte phase III data in HS

March 17, 2025
By Randy Osborne
Investors wanted more from Incyte Corp.’s top-line results in hidradenitis suppurativa (HS) from its pivotal phase III Stop-HS trial program with oral small-molecule JAK1 inhibitor povorcitinib in adults with moderate to severe disease. Shares of the Wilmington, Del.-based firm (NASDAQ:INCY) closed March 17 at $62.01, down $5.85, after the company made public that Stop-HS1 and Stop-HS2 met the primary endpoint at both tested doses (45 mg and 75 mg)
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Art concept for inflamed human tissue

Time nigh for I&I? Key data points ahead

March 11, 2025
By Randy Osborne
Yesterday’s first part of this two-part series surveyed bispecific antibodies for immunological and inflammatory (I&I) disease. Apart from bispecifics, Leerink analyst Thomas Smith lately has proven interested in I&I overall, unveiling his “five for 2025” in a January report that listed five indications with “potential for disruption” in the year ahead.
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Skin exam
Immune

Photys licenses rights to Polymed’s IRAK-4 degrader

Feb. 21, 2025
Photys Therapeutics Inc. has signed a license agreement with Hangzhou Polymed Biopharmaceuticals Inc. for HPB-143, a phase I-ready IRAK-4 degrader. IRAK-4 degradation offers potential to treat various autoimmune indications, including atopic dermatitis and hidradenitis suppurativa.
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Citryll raises €85M series B to advance CIT-013 into phase II

Dec. 9, 2024
By Nuala Moran
Citryll BV has closed an €85 million (US$89.8 million) series B, enabling it to take CIT-013, an antibody designed to block pathological neutrophil extracellular traps that drive a wide range of immune-mediated inflammatory diseases, into phase IIa development.
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Hidradenitis suppurativa illustration

UCB chalks hidradenitis suppurativa as fifth indication for Bimzelx

Nov. 20, 2024
By Randy Osborne
The U.S. FDA added hidradenitis suppurativa to the label for UCB SA’s Bimzelx (bimekizumab-bkzx), throwing renewed light on the indication, a chronic disease that causes painful, boil-like lumps that appear under the skin. Regulators cleared the humanized IL-17A and IL-17F antagonist for adults with moderate to severe HS, marking the drug’s fifth approval.
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Global handshake silhouette

Huadong gets China rights to Imbiologics’ Oxtima program for ₩430B

Aug. 27, 2024
By Marian (YoonJee) Chu
Imbiologics Inc. scored a potential ₩430 billion (US$315.5 million) deal with China’s Hangzhou Zhongmei Huadong Pharmaceutical Co. Ltd. for Oxtima, an autoimmune disease program with two assets co-developed by Seoul, South Korea-based HK Inno.N Corp.
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Global handshake silhouette

Huadong gets China rights to Imbiologics’ Oxtima program for ₩430B

Aug. 20, 2024
By Marian (YoonJee) Chu
Imbiologics Inc. scored a potential ₩430 billion (US$315.5 million) deal with China’s Hangzhou Zhongmei Huadong Pharmaceutical Co. Ltd. for Oxtima, an autoimmune disease program with two assets co-developed by Seoul, South Korea-based HK Inno.N Corp.
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Global handshake silhouette

Huadong gets China rights to Imbiologics’ Oxtima program for ₩430B

Aug. 19, 2024
By Marian (YoonJee) Chu
Imbiologics Inc. scored a potential ₩430 billion (US$315.5 million) deal with China’s Hangzhou Zhongmei Huadong Pharmaceutical Co. Ltd. for Oxtima, an autoimmune disease program with two assets co-developed by Seoul, South Korea-based HK Inno.N Corp.
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Face with digital focus on eye

HS dropout as math favors Acelyrin’s TED course with lonigutamab

Aug. 14, 2024
By Randy Osborne
With favorable data from the phase III trial testing izokibep, a small protein therapeutic designed to inhibit IL-17A, in hidradenitis suppurativa (HS), Acelyrin Inc. CEO Mina Kim said the firm will “look at all the options and do what’s best for the program.” The phase III trial hit its primary endpoint of Hidradenitis Suppurativa Clinical Response 75 at 12 weeks. At the same time, the Los Angeles-based firm made known a refocused pipeline strategy that prioritizes lonigutamab in thyroid eye disease (TED) and is projected to extend its cash runway.
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3D rendering of skin cells and elastin with collagen layer
Biomarkers

PRO-C22 identified as marker of severity and activity in hidradenitis suppurativa

March 13, 2024
Hidradenitis suppurativa (HS) is an inflammatory skin disease with significant diagnostic delay. Type XXII collagen is a fibrillar collagen located in the skin epidermis. Reliable biomarkers to aid in the diagnosis of HS and monitor the severity of disease are needed.
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