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Home » Keywords » Aligos Therapeutics Inc.

Items Tagged with 'Aligos Therapeutics Inc.'

ARTICLES

Coronavirus variants
Infection

ALG-097558 confirmed as an effective pan-coronavirus strategy

March 17, 2025
Although safe and effective vaccines for SARS-CoV-2 have been successfully developed, there are currently no therapeutic approaches available for treating acute infection, particularly for individuals at high risk of severe disease progression, and for preparedness against a potential new coronavirus pandemic.
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Immuno-oncology

Aligos Therapeutics patents new inhibitors of PD-1, PD-L1 or PD-1/PD-L1 interaction

Feb. 4, 2025
Aligos Therapeutics Inc. has disclosed programmed cell death 1 (PDCD1; PD-1; CD279) and/or PD-1 ligand 1 (PD-L1; CD274) and/or PD-1/PD-L1 interaction inhibitors reported to be useful for the treatment of hepatocellular carcinoma and hepatitis B.
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Liver over digital lens background

Hark, Herald MASH phase II positive but Aligos THRown for a loop

Sep. 19, 2024
By Randy Osborne
After disclosing data from the phase II Herald study, Aligos Therapeutics Inc. may sign a partner to help advance ALG-055009, a thyroid hormone receptor (THR) beta agonist, in subjects with metabolic dysfunction-associated steatohepatitis (MASH, formerly nonalcoholic steatohepatitis, or NASH).
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Cancer

Aligos Therapeutics presents new PD-1/PD-L1 interaction inhibitors

Aug. 13, 2024
Aligos Therapeutics Inc. has described programmed cell death 1 (PDCD1; PD-1; CD279)/PD-1 ligand 1 (PD-L1; CD274) interaction inhibitors reported to be useful for the treatment of liver cancer (hepatocellular carcinoma) and hepatitis B.
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Hepatitis B virus
Infection

Novel CAM-A candidates show rapid HBsAg reductions in vivo

June 21, 2024
Aligos Therapeutics Inc. have discovered two novel non-heteroaryldihydropyrimidine (HAP) class A capsid assembly modulators (CAM-A) – ALG-006746 and ALG-006780 – which are being developed for the treatment of hepatitis B virus (HBV) infection.
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Infection

Aligos and KU Leuven synthesize new Mpro inhibitors

May 29, 2024
Aligos Therapeutics Inc. and Katholieke Universiteit Leuven (KU Leuven ) have jointly developed new 3C-like proteinase (3CLpro; Mpro; nsp5) (SARS-CoV-2; COVID-19 virus) inhibitors reported to be useful for the treatment of SARS-CoV-2 infection (COVID-19), rhinovirus and norovirus infections.
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Infection

Aligos Therapeutics describes new prodrugs to treat hepatitis B and D virus infections

April 22, 2024
Aligos Therapeutics Inc. has identified prodrugs reported to be useful for the treatment of hepatitis B and hepatitis D viral infections.
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Infection

Mpro inhibitors described in joint Aligos Therapeutics and Katholieke Universiteit Leuven patent

Feb. 6, 2024
Aligos Therapeutics Inc. and Katholieke Universiteit Leuven have jointly patented 3C-like proteinase (3CLpro; Mpro; nsp5) (SARS-CoV-2; COVID-19 virus) inhibitors for the treatment of SARS-CoV-2 infection (COVID-19), middle East respiratory syndrome coronavirus (MERS-CoV) infection, norovirus and rhinovirus infections.
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3D print imagery of hepatitis B virus
Infection

ALG-001075 demonstrates promising preclinical resistance profile

Nov. 20, 2023
Researchers from Aligos Therapeutics Inc. presented preclinical data for ALG-001075, a novel capsid assembly modulator leading to the formation of empty capsids (CAM-E), being developed for the treatment of hepatitis B.
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Infection

Aligos Therapeutics presents new viral replication inhibitors for hepatitis B and D

Nov. 16, 2023
Aligos Therapeutics Inc. has divulged bicyclic compounds acting as viral replication inhibitors reported to be useful for the treatment of hepatitis B (HBV) and hepatitis D virus infections.
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More Articles Tagged with 'Aligos Therapeutics Inc.'

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