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BioWorld - Wednesday, July 16, 2025
Home » Keywords » chikungunya

Items Tagged with 'chikungunya'

ARTICLES

Chikungunya-virus
Index insights

Chikungunya wins boost Valneva; overall infectious disease stocks fall

May 22, 2025
By Amanda Lanier
No Comments
Infectious disease stocks stumbled in the early months of 2025, with the BioWorld Infectious Disease Index (BIDI) plunging 17.83% by the end of April, well behind the broader markets. By comparison, the Nasdaq Biotechnology Index slipped just 1.16%, and the Dow Jones Industrial Average declined 4.41%. In 2024, the BIDI ended the year down 6.28%, after hitting a low of -25.12% in late April.
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FDA vaccine illustration

FDA approves vaccines for chikungunya, meningococcal disease

Feb. 18, 2025
By Lee Landenberger
Infection

OHSU and the Southern Research Institute identify new inhibitors of alphaviruses

Nov. 7, 2024
Oregon Health and Science University (OHSU) and the Southern Research Institute have patented compounds reported to be useful for the treatment of alphaviral infections.
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CHMP: Re-eval for Translarna; recommendation for Ixchiq, Cejemly

June 3, 2024
By Nuala Moran
The EMA has been sent back to the drawing board to re-evaluate PTC Therapeutics Inc.’s Duchenne muscular dystrophy therapy Translarna (ataluren), after failing to get the usual rubber stamp following its recommendation in January that the drug’s conditional approval be withdrawn.
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Immune

Emergex to support T cell-based Chikungunya vaccine candidate

Nov. 20, 2023
Emergex Vaccines Holding Ltd. has signed a contract with the U.K. Department of Health and Social Care (DHSC) for almost £1.8 million (US$2.2 million) to advance a CD8 T cell-based vaccine candidate against Chikungunya virus (CHIKV).
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ACIP next as FDA clears Valneva chikungunya vaccine

Nov. 10, 2023
By Randy Osborne
With Valneva SE’s accelerated approval from the U.S. FDA for chikungunya vaccine Ixchiq, attention turned to the February 2024 meeting of the Advisory Committee on Immunization Practices (ACIP), which will vote on the product. A single-dose, live-attenuated vaccine, Ixchiq is designed to prevent disease caused by the virus in people 18 and older who are at increased risk of exposure to the bug.
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Teen receiving vaccine

CHIKV vaccine fever on rise as Valneva phase III follows Bavarian Nordic data

Aug. 28, 2023
By Randy Osborne
About two weeks after chikungunya virus (CHIKV) vaccine contender Bavarian Nordic A/S provided phase III data with its prospect, rival Valneva SE rolled out positive phase III safety findings in adolescents with its single-dose candidate VLA-1553. Results from the Saint-Herblain, France-based company’s first trial in an endemic area with people previously infected with CHIKV showed the product was generally safe and well-tolerated in subjects aged 12-17 years, regardless of previous infection by the mosquito-borne disease, carried mainly by Aedes aegypti and Aedes albopictus. Immunogenicity data from the study are expected in November.
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Chikungunya-virus

One in, one out: Bavarian Nordic prepares chikungunya filing as RSV vaccine falls by wayside

Aug. 7, 2023
By Caroline Richards
The dent made in Bavarian Nordic A/S’ future revenues after it dropped development of late-stage respiratory syncytial virus (RSV) contender MVA-BN-RSV could be offset by potential sales of its chikungunya virus vaccine, PXVX-0317, if recent phase III immunogenicity data manage to persuade the U.S. FDA that it’s as worthy as Valneva SA’s VLA-1553, the other chikungunya vaccine racing to be first to market.
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Vivotif-and-Vaxchora.png

Have deal, will travel: Bavarian Nordic buys vaccines from Emergent Biosolutions

Feb. 15, 2023
By Lee Landenberger
Bavarian Nordic A/S plans to buy two travel vaccines plus a phase III chikungunya vaccine candidate from Emergent Biosolutions Inc. for about $380 million. Emergent will receive a $270 million up-front payment and perhaps as much as $110 million in future milestone payments. The vaccines are Vivotif, for preventing typhoid fever, and Vaxchora, for preventing cholera caused by Vibrio cholerae serogroup O1. Both oral vaccines have U.S. FDA and European approvals.
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Valneva posts positive chikungunya vaccine data

Dec. 5, 2022
By Lee Landenberger
Twelve months after a single shot of Valneva SE’s chikungunya vaccine, positive antibody persistence was found, threatening a deadly disease that has long resisted treatment. The new data are derived from a study of 363 healthy adult participants that followed them from month 6 after vaccination to month 12. Nearly all, 99%, kept their neutralizing antibody titers for 12 months beyond the seroresponse threshold of 150, which hit the primary endpoint and the antibody level agreed with regulators as endpoint under the accelerated approval pathway.
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