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Home » Keywords » Cas9

Items Tagged with 'Cas9'

ARTICLES

Heavy methyl: Chroma Medicine closes $135M series B round for epigenetic editing

March 1, 2023
By Cormac Sheridan
Chroma Medicine Inc. closed a $135 million series B round as momentum builds at one of the early movers in the emerging field of epigenetic editing. It’s little more a year since Cambridge, Mass.-based Chroma emerged from stealth by disclosing a $125 million series A round and a stellar line-up of company founders. “It’s not all that long ago, but we have made a huge amount of progress,” CEO Catherine Stehman-Breen told BioWorld.
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Handshake with DNA, molecules

Scribe, Vertex add to gene therapy's advance with $1B+ deal, near-term BLA

Sep. 27, 2022
By Michael Fitzhugh
CRISPR-based cell therapies continued to gain steam Sept. 27 with the announcements of a potentially valuable big pharma collaboration and an ambitious global regulatory push.
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CRISPR Cas9 illustration

Ers Genomics granted CRISPR-Cas9 patent in China

Nov. 23, 2021
By Doris Yu
A Chinese patent covering methods and compositions for the use of CRISPR-Cas9 in eukaryotes has been granted to Dublin-based Ers Genomics Ltd., making what Michael Arciero, vice president of intellectual property and commercial development at the company, called “a strong but not surprising statement by China,” which has made the biotechnology industry one of its top national priorities.
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Ers Genomics granted CRISPR-Cas9 patent in China

Nov. 18, 2021
By Doris Yu
A Chinese patent covering methods and compositions for the use of CRISPR-Cas9 in eukaryotes has been granted to Dublin-based Ers Genomics Ltd., making what Michael Arciero, vice president of intellectual property and commercial development at the company, called “a strong but not surprising statement by China,” which has made the biotechnology industry one of its top national priorities.
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Chroma Medicine closes $125M A round for epigenetic editing platform

Nov. 17, 2021
By Cormac Sheridan
Chroma Medicine Inc. emerged from stealth with $125 million in series A financing and high ambitions to rewrite the rules of genomic medicine by modulating the epigenetic status of target genes in order to switch expression on or off and thereby achieve therapeutic outcomes.
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Amyloid plaque on nerve cell

In vivo gene editing alleviates amyloid pathologies

Aug. 3, 2021
By John Fox
Brain-wide genome editing via a single systemic dose of modified adeno-associated virus variants that cross the blood-brain barrier may represent a promising new approach for the development of disease-modifying treatments for familial Alzheimer's disease. This strategy could also be applicable to other central nervous system (CNS) disorders, according to a proof-of-concept (PoC) study led by researchers at The Hong Kong University of Science and Technology (HKUST).
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Amyloid plaque on nerve cell

In vivo gene editing alleviates amyloid pathologies

July 30, 2021
By John Fox
Brain-wide genome editing via a single systemic dose of modified adeno-associated virus variants that cross the blood-brain barrier may represent a promising new approach for the development of disease-modifying treatments for familial Alzheimer's disease.
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Gene editing illustration

Scribe closes $100M series B round for gene editing rewrite

March 31, 2021
By Cormac Sheridan
Scribe Therapeutics Inc. raised $100 million in a series B round to continue its engineering-intensive approach to developing CRISPR-based therapies that employ custom-designed CasX enzymes.
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Nobel Prize in Chemistry illustration
Three’s a crowd?

Doudna-Charpentier duo is sole winner of chemistry Nobel

Oct. 7, 2020
By Anette Breindl
Surprising no one, Jennifer Doudna and Emmanuelle Charpentier won the 2020 Nobel Prize in Chemistry “for the development of a method for genome editing,” that is, the CRISPR/Cas9 system.
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