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Home » Keywords » Inmazeb

Items Tagged with 'Inmazeb'

ARTICLES

Illustration of 3 different antibodies binding to Ebola virus glycoprotein.
Infection

Bringing out asymmetries deepens understanding of Ebola drug

Feb. 7, 2023
By Mar de Miguel
Using a near-atomic resolution cryo-electron microscope and imaging techniques that prevent loss of information, scientists at the La Jolla Institute for Immunology (LJI) and Regeneron Pharmaceuticals Inc. have obtained the complete 3D structure of the glycoprotein of the Ebola virus and that of the drug that neutralizes it, Inmazeb, the first FDA-approved treatment for this deadly virus. “The challenge was embracing the inherent asymmetry, the heterogeneity that is really there in biology, understanding it and collecting enough data to get all the images without needing to force any symmetry averaging,” senior author Erica Ollmann Saphire told BioWorld.
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Ebola virus

Ebola losing ‘killer’ status to MAbs

Aug. 22, 2022
By Mari Serebrov
Regeneron Pharmaceuticals Inc.’s Inmazeb and Ridgeback Biotherapeutics LP’s Ebanga earned a ringing endorsement from the World Health Organization (WHO) in its first ever guideline on Ebola therapies. In releasing the guideline Aug. 19, WHO officials celebrated the fact that Ebola is no longer “a near certain killer” – provided treatment starts as soon as possible following diagnosis.
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FDA Approved stamp with pills, bottle, blister pack

FDA approves record number of NMEs in 2020

Jan. 26, 2021
By Peter Winter
Following the FDA giving the green light to seven new medicines in December, it brought the approval total of new molecular entities (NMEs) in 2020 to 53, an amount that equals the number of new medicines that were approved in 1996 and ranking it second equal all-time just behind the 59 NMEs that were approved in 2018.
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Regeneron’s triple-antibody cocktail receives first FDA approval for treating Ebola

Oct. 15, 2020
By Lee Landenberger
In Regeneron Pharmaceuticals Inc.’s Inmazeb (atoltivimab, maftivimab and odesivimab-ebgn), the FDA has approved its first ever treatment for the Ebola virus in pediatric and adult patients.
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