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Home » Keywords » Seagen Inc.

Items Tagged with 'Seagen Inc.'

ARTICLES

Golden dollar coins
Analysis

Few biopharma mega-mergers hit the jackpot

Feb. 5, 2025
By Karen Carey
Due diligence plays a significant role in M&A transactions, but the eventual return on investments don’t always add up to the purchase price. While some companies such as Abbvie Inc. and Bristol Myers Squibb Co. – as shown in part one of this three-part series – have succeeded in acquiring products able to surpass M&A sticker prices, the vast majority of deals analyzed by BioWorld showed that most buyers remain significantly in the red.
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Cancer

Sanofi and Seagen patent CEACAM5 antibody-drug conjugates

June 13, 2024
Sanofi SA and Seagen Inc. have reported antibody-drug conjugates comprising antibodies targeting carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5; CEA; CD66e) covalently linked to topoisomerase I inhibitors through a linker reported to be useful for the treatment of cancer.
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Affimed, Seagen soldiers in long SWOG for Hodgkin lymphoma drugs

March 21, 2024
By Randy Osborne
The Hodgkin lymphoma space found itself in the spotlight late last year when Affimed NV rolled out updated data with lead innate cell engager acimtamig when combined with allogeneic natural killer cells. Findings from the investigator-initiated trial became the topic of talk at the American Society of Hematology meeting, when Yago Nieto, professor at the University of Texas MD Anderson Cancer Center – and principal investigator of the study – spoke.
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Handshake with dollar sign and checkmark
Biopharma deals 4Q24

Larger value, fewer transactions: biopharma deals up modestly while M&As soar 80% in 2023

Jan. 16, 2024
By Amanda Lanier
The landscape of biopharma deals and M&As has seen a transformative shift, with a year-over-year drop in transaction numbers while value has increased. Overall, biopharma deals saw an uptick in value of nearly 6%, and biopharma M&As concurrently soared 80% higher in value than the previous year.
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Top Trends Therapeutics, pill, syringe

Industry learning its ADCs better and better as deals abound

Dec. 29, 2023
By Randy Osborne
Pharma-biotech pairings continued apace in the antibody-drug conjugate (ADC) space, with 2023 capped by Legochem Biosciences Inc. signing a $1.7 billion licensure deal with Johnson & Johnson arm Janssen Biotech Inc. for the former’s Trop2-directed compound, the second-biggest Korean technology transfer agreement.
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Cancer cell
BioWorld Cancer Index (BCI)

BCI flourishes despite widespread stock declines

Nov. 1, 2023
By Amanda Lanier
The BioWorld Cancer Index (BCI) saw its highest point of the year from April through July, when it had a run above 30%, before falling to 23.5% at the end of August. It closed Q3 up 22.96% for the year, a sharp divergence from the more extensive Nasdaq Biotechnology Index and Dow Jones Industrial Average, which are tracking down 6.16% and up 1.09%, respectively.
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Cancer

CD30-directed antibody-drug conjugate SGN-35T for the treatment of lymphoma

Oct. 20, 2023
Antibody-drug conjugates (ADCs) are effective anti-cancer agents in a wide variety of solid and hematologic cancers. CD30 (TNFRSF8), a member of the TNF receptor superfamily is the target of antibody drug conjugate Adcetris (brentuximab vedotin/BV, Seagen Inc.) approved for use in multiple CD30-expressing lymphomas.
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Scientist, microscope and dropper

In a cancer development deal with Seagen, Nurix could bring in up to $3.4B

Sep. 7, 2023
By Lee Landenberger
In a mammoth deal with a potentially huge payoff, Nurix Therapeutics Inc. and Seagen Inc. will collaborate to develop what they call a new class of medicines, Degrader-Antibody Conjugates, to create drugs with new mechanisms of action for treating cancer.
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Approved stamp

Armed with new tools, US FDA picks up pace of accelerated approvals

May 12, 2023
By Mari Serebrov
Despite congressional concerns about accelerated approval, the U.S. FDA’s use of the pathway is not slowing down. If anything, it’s picked up pace since Congress gave the agency stronger authority last year to monitor drugs approved based on a surrogate endpoint and to ensure that confirmatory trials are progressing in a timely way.
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FDA approves anti-PD-1/ADC combo for urothelial cancer

April 4, 2023
By Lee Landenberger
As Seagen Inc. preps for a merger, the U.S. FDA awarded accelerated approval to the company’s big-selling Padcev (enfortumab vedotin). The approval is for a combination therapy with Merck & Co. Inc.’s Keytruda (pembrolizumab) as a first-line treatment for adults with locally advanced or metastatic urothelial cancer who are not eligible for cisplatin-containing chemotherapy.
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More Articles Tagged with 'Seagen Inc.'

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