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Home » Keywords » systemic autoimmune diseases

Items Tagged with 'systemic autoimmune diseases'

ARTICLES

3D illustration of the Anakinra molecular structure
Hematologic

Edited blood stem cells dampen disordered inflammation

June 8, 2023
By Anette Breindl
Researchers have ameliorated both monogenic and complex inflammation-driven diseases through transplantation of hematopoietic stem cells with an inserted IL-1 receptor antagonist (IL-1RA) gene. The team showed that in animal models the transplanted cells worked better than monoclonal antibodies to reduce symptoms in systemic autoinflammatory diseases (SAIDs), a group of childhood-onset, lifelong diseases that vary in severity depending on the underlying mutation, but can be life-threatening.
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Antibody

Antibodies target fibrotic and autoimmune diseases

Jan. 11, 2021
By John Fox
A Sino-U.S. study has shown that the increased expression of the small secreted glycoprotein follistatin-like 1 is critical in the pathogenesis of multiple fibrotic and systemic autoimmune diseases, the authors reported in the January 6, 2021, print edition of Molecular Therapy after earlier publication online.
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