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Home » Keywords » CD8

Items Tagged with 'CD8'

ARTICLES

Neurology/Psychiatric

Reverse translational study of anti-CD20 treatment on T and B cells and their interactions in MS

Feb. 24, 2023
The use of anti-CD20 therapies has revolutionized treatment options for multiple sclerosis (MS) patients, reducing relapses and halting disease progression. While CD20 is primarily expressed by B cells at different stages, a small T-cell subset also expresses CD20, and therefore anti-CD20 therapies also directly and indirectly affect T cells.
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Pharma serenades Mozart as three biggies join $55M series A for CD8 push

Oct. 26, 2021
By Randy Osborne
Mozart Therapeutics Inc. CEO Katie Fanning said the firm’s $55 million series A financing will allow the filing of an IND, probably in early 2024, for a prospect in celiac disease. Founded in July 2020, Seattle-based Mozart is based on research into the CD8 T-cell regulatory network, which has been found to play an important role in surveillance, recognition and elimination of inappropriately activated autoreactive and pathogenic immune cells.
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Cancer cell and DNA

Gut microbial metabolites facilitate anticancer therapy

March 30, 2021
By John Fox
A study led by Chinese scientists at Tsinghua University in Beijing has demonstrated that the gut microbial metabolite butyrate can directly modulate the antitumor CD8 "killer" T-cell response and improve chemotherapy efficacy through ID2-dependent IL-12 signaling.
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