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Home » Keywords » H. pylori

Items Tagged with 'H. pylori'

ARTICLES

Concept art for H. pylori infection and gastric cancer risk
Cancer

Nature, nurture, DNA damage contribute to H. pylori’s effects on gastric cancer

April 5, 2023
By Anette Breindl
Helicobacter pylori infection and germline genetic variants interacted with each other to affect the risk of gastric cancer in a study comparing more than 11,000 patients with stomach cancer and 44,000 people without cancer. Researchers from the RIKEN Center for Integrative Medical Sciences (IMS) published those findings in the March 30, 2023, issue of the New England Journal of Medicine.
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Galen Gastric concept image

Ibex unveils Galen AI gastric cancer detection system

Aug. 31, 2021
By Nuala Moran
LONDON – Ibex Medical Analytics Ltd. has claimed a further advance in applying artificial intelligence (AI) to the interpretation of digitized pathology slides, reporting that the first commercial system in the world using AI to detect gastric cancers has gone live. The Galen Gastric system has been deployed at the pathology lab of Maccabi Healthcare Services, one of Israel’s leading HMOs, where it is now operational alongside Ibex’s breast and prostate cancer AI systems.
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Stomach, H. pylori

H. pylori oncoprotein-induced genome instability may underlie gastric cancer

May 14, 2021
By John Fox
A Japanese study has found that the Helicobacter pylori oncoprotein, CagA, elicited transient 'BRCAness', inducing genomic instability via DNA double-strand breaks and defective homologous recombination. The effects may underlie the gastric carcinogenesis associated with chronic H. pylori infection.
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Stomach, H. pylori

Path of least resistance: Talicia wins in H. pylori, Redhill launch next year

Nov. 5, 2019
By Randy Osborne
Redhill Biopharma Ltd. CEO Dror Ben-Asher told BioWorld that the 2 million patients targeted by just-approved, delayed-release Talicia, previously known as RHB-105, for adult infection by Helicobacter pylori represents "the baseline where we start our promotion," and there's an opportunity to help many more patients. "When you combine the high prevalence of roughly 100 million Americans infected and more than half of the world's population with the association with gastric cancer, it's a major public health concern," he said. About 800,000 people worldwide die every year from gastric cancer, and about 90% of cases are caused by H. pylori.
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