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Home » Keywords » Corbus Pharmaceuticals Holdings Inc.

Items Tagged with 'Corbus Pharmaceuticals Holdings Inc.'

ARTICLES

Nectin-4 the win? Corbus fronts Western phase I with ADC

Feb. 14, 2025
By Randy Osborne
Corbus Pharmaceuticals Inc. has placed its chips on “bets where somebody else is ahead of us,” CEO Yuval Cohen said. “The idea is to have a de-risked asset” that proves better in the clinic. At the 2025 American Society of Clinical Oncology Genitourinary (ASCO GU) Cancers Symposium in San Francisco, Corbus offered data from the U.S. and U.K. first-in-human dose-escalation study – the Western trial – with Nectin-4-targeting antibody-drug conjugate (ADC) CRB-701 (SYS-6002).
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Endocrine/metabolic

Corbus presents peripherally restricted CB1 inverse agonist

Nov. 7, 2024
Cannabinoid receptor type 1 (CB1) blockers have been shown to attenuate diet-induced obesity.
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Pills, bottle, scale and-measuring tape

Recovery room: Skye, Corbus mend post-Novo CB1 weight-loss data

Sep. 23, 2024
By Randy Osborne
What the results might mean for the future of other developers in the cannabinoid receptor 1 (CB1) weight-loss arena came into question after Novo Nordisk A/S unveiled phase IIa findings with monlunabant, a small-molecule oral inverse agonist, formerly INV-202.
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ADCs lead the data charge at ASCO while AI shapes the landscape

June 4, 2024
By Lee Landenberger
While there was much talk about the vast potential of artificial intelligence (AI) during one of the world’s largest research cancer conferences, antibody-drug conjugates (ADCs) continued to grab the lion’s share of attention as Corbus Pharmaceuticals Holdings Inc. and Takeda Pharmaceutical Co. Ltd. released new and positive data.
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ADCs lead the data charge at ASCO while AI shapes the landscape

June 3, 2024
By Lee Landenberger
While there was much talk about the vast potential of artificial intelligence (AI) during one of the world’s largest research cancer conferences, antibody-drug conjugates (ADCs) continued to grab the lion’s share of attention as Corbus Pharmaceuticals Holdings Inc. and Takeda Pharmaceutical Co. Ltd. released new and positive data.
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3D rendering of drug linked to antibody

Corbus rockets on early clinical data for next-gen Nectin-4 ADC candidate

Jan. 26, 2024
By Jennifer Boggs
Shares of Corbus Pharmaceuticals Inc. (NASDAQ:CRBP) doubled on opening Jan. 26 and ended the day up a whopping 249% as investors got a look at data from a first-in-human study testing next-generation Nectin-4-targeted antibody-drug conjugate (ADC) CRB-701. Licensed from CSPC Pharmaceutical Group for $7.5 million up front in February 2023, CRB-701 has IND clearance from the U.S. FDA, and Corbus plans to start its own clinical testing in the first quarter of 2024.
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Art concept for monoclonal antibodies
Immuno-oncology

Corbus gains IND clearance for anti-αvβ8 monoclonal antibody

Jan. 10, 2024
Corbus Pharmaceuticals Holdings Inc. has obtained FDA clearance of its IND application for CRB-601, a TGF-β-blocking monoclonal antibody targeting the integrin αvβ8. Enrollment in a first-in-human phase I study will open in the first half of this year.
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Endocrine/Metabolic

Corbus Pharmaceuticals discovers new cannabinoid CB1 receptor antagonists

Nov. 3, 2023
Corbus Pharmaceuticals Holding Inc. has described cannabinoid CB1 receptor antagonists or inverse agonists reported to be useful for the treatment of cancer, dyslipidemia, diabetes, obesity, cardiovascular, inflammatory and liver diseases.
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Global handshake silhouette

After Padcev, Corbus ‘Nectin’ line? Potential $692M-plus CSPC deal brings phase I prospect aboard

Feb. 14, 2023
By Randy Osborne
Corbus Pharmaceuticals Holdings Inc. signed a back end-loaded licensing deal worth up to $692.5 million with CSPC Megalith Biopharmaceutical Co. Ltd, a subsidiary of CSPC Pharmaceutical Group Ltd., for the latter’s Nectin-4-targeting antibody-drug conjugate CRB-701 (SYS-6002).
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Global handshake silhouette

After Padcev, Corbus ‘Nectin’ line? Potential $692M-plus CSPC deal brings phase I prospect aboard

Feb. 13, 2023
By Randy Osborne
Corbus Pharmaceuticals Holdings Inc. signed a back end-loaded licensing deal worth up to $692.5 million with CSPC Megalith Biopharmaceutical Co. Ltd, a subsidiary of CSPC Pharmaceutical Group Ltd., for the latter’s Nectin-4-targeting antibody-drug conjugate CRB-701 (SYS-6002).
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More Articles Tagged with 'Corbus Pharmaceuticals Holdings Inc.'

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