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Home » Keywords » neural progenitor cell

Items Tagged with 'neural progenitor cell'

ARTICLES

Elderly woman holding illustration of brain with missing puzzle piece
Neurology/Psychiatric

iNPC-GDNFs show promise as a combined cell and gene therapy for neurodegenerative diseases

May 9, 2023
Replacing the damaged cell population in neurodegenerative diseases provides a treatment approach. However, interventions that protect host cells could offer new treatment possibilities for neurodegenerative diseases, such as Parkinson’s and Alzheimer’s diseases and amyotrophic lateral sclerosis (ALS).
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3D illustration of chromosomes

Down syndrome linked to senescence-like state

Jan. 10, 2022
By John Fox
Trisomy 21, the abnormal third copy of chromosome 21 causing developmental disorders in Down syndrome, has been shown to promote reorganization of the entire neural progenitor cell (NPC) genome, with the resulting gene transcription and cell function disruption being so similar to senescence that anti-senescence drugs could correct them in cell cultures.
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