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Home » Keywords » Streptococcus pneumoniae

Items Tagged with 'Streptococcus pneumoniae'

ARTICLES

Drug Design, Drug Delivery & Technologies

Synthetic antibiotics pack multiple punches against gram-positive bacteria

July 13, 2023
By Mar de Miguel
A chance discovery has led to a new class of antibiotics with multiple arms that interacted with the cell wall of gram-positive bacteria, inhibiting their assembly and disarming them. “It was an accidental discovery. We were using it to stain cells. We also were running evaluations of antibiotics. One of my former students came to me and said: ‘I think we have discovered something that is quite potent as an antibiotic,’” the senior author Xingyu Jiang told BioWorld.
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Infection

Bacterial meningitis invades the brain by repressing the immune system through pain receptors

March 6, 2023
By Mar de Miguel
Bacteria inflaming the meninges have developed an immunosuppressive mechanism that contributes to their ability to attack the brain. Researchers found that, by activating pain receptors (nociceptors) to release chemical substances that block an immune cell receptor, Streptococcus pneumoniae and Streptococcus agalactiae deactivated the protective function of macrophages and weakened brain defenses. This, in turn, enabled them to invade the brain.
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Streptococcus pneumoniae in lungs

Researchers restore front-line antibiotics' effects

Jan. 13, 2022
By Tamra Sami
Researchers at the Peter Doherty Institute for Infection and Immunity, the University of Queensland, Griffith University, the University of Adelaide and St. Jude Children's Research Hospital have unlocked a key to making existing front-line antibiotics work again against Streptococcus pneumoniae, the bacteria that cause pneumonia.
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