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Home » Keywords » WNT5A

Items Tagged with 'WNT5A'

ARTICLES

Acute myeloid leukemia
Cancer

Foxy-5 as an antineoplastic agent with efficacy in models of AML

July 6, 2023
It has been previously demonstrated that the WNT gene/protein family member WNT5A is down-regulated in leukemia, and low expression of this tumor suppressor has been correlated with disease progression and poor prognosis. In a recent study, researchers from Universidade Estadual de Campina aimed to assess the role of WNT5A in leukemia and evaluate the effects of Foxy-5, (Wntresearch AB) a WNT5A-mimicking compound, on the progression of this disease.
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WNT plays dual role in melanoma spread to lung

June 8, 2022
By Anette Breindl
Researchers have long known that the developmental regulator WNT5A plays a role in the dissemination of tumor cells. Now, investigators from Johns Hopkins University have discovered that its suppression plays a role in the growth of metastases after a period of dormancy as well.
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