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Home » Keywords » Pretzel Therapeutics Inc.

Items Tagged with 'Pretzel Therapeutics Inc.'

ARTICLES

Art concept for gene therapy research
Genetic/congenital

Pretzel Therapeutics narrows the therapeutic gap for PolG disease

April 15, 2025
By Xavier Bofill Bruna
Researchers from Pretzel Therapeutics Inc. and the University of Gothenburg have published new insights on how mutations in the POLG gene affect its functionality and are tied to PolG diseases. They have also presented a compound for its potential treatment, PZL-A. They published their results in Nature on April 9, 2025.
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Neurology/psychiatric

Pretzel Therapeutics patents new POLG modulators

Feb. 3, 2025
Pretzel Therapeutics Inc. has disclosed DNA polymerase subunit γ-1 (POLG) modulators reported to be useful for the treatment of neurodegeneration and mitochondrial diseases.
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Cancer

Pretzel Therapeutics divulges LONP1 inhibitors

July 5, 2023
Pretzel Therapeutics Inc. has patented heterocycle-containing compounds acting as Lon protease homolog, mitochondrial (LONP1) inhibitors. They are reported to be useful for the treatment of cancer, aging, neurodegeneration and metabolic diseases.
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Mitochondria illustration
Genetic/congenital

Pretzel Therapeutics launches with focus on mitochondrial biology

Sep. 13, 2022
Pretzel Therapeutics Inc. has launched with a $72.5 million series A financing to pioneer novel therapies to modulate mitochondrial function to treat rare genetic diseases and common diseases of aging.
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