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BioWorld - Tuesday, May 13, 2025
Home » Keywords » FGF21

Items Tagged with 'FGF21'

ARTICLES

Cardiovascular

FGF21 protects mice from ischemic stroke, study shows

March 12, 2025
Ischemic stroke is a fatal condition caused by an arterial embolism that blocks the blood flow through the cerebral artery, frequently being a cause of mortality and disability. Fibroblast growth factor 21 (FGF21) is likely the only member of the FGF family that may cross the blood-brain barrier. Among its functions, inflammatory regulation, energy metabolism, vascular homeostasis, oxidative stress and tissue repair can be highlighted.
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89bio’s phase IIb outcome Enlivens NASH space, whets enthusiasm for phase III

March 22, 2023
By Randy Osborne
89bio Inc.’s top-line phase IIb data from the 216-subject study called Enliven testing pegozafermin in nonalcoholic steatohepatitis (NASH) pushed shares (NASDAQ:ETNB) to a closing price March 22 of $13.68, up $2.75, or 25%. The drug, due next for phase III investigation, is a glycopegylated analogue of fibroblast growth factor 21.
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Biomarkers

Identifying mitokines as potential biomarkers in Rett syndrome

March 17, 2023
Rett syndrome (RTT) is a severe, neurodevelopmental disorder that occurs due to pathogenic variants in the methyl-CpG-binding...
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Liver illustration

Akero skyrockets on midstage data from NASH challenger efruxifermin

Sep. 13, 2022
By Richard Staines
Shares in Akero Therapeutics Inc. more than doubled in value after the company announced results from a phase IIb nonalcoholic steatohepatitis trial that it believes show lead candidate efruxifermin could challenge other candidates in development for the fatty liver disease targeted by so many biotechs and big pharmas.
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