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Home » Keywords » Mat2A inhibitors

Items Tagged with 'Mat2A inhibitors'

ARTICLES

Cancer

Euregen Biopharma divulges new Mat2A inhibitors

July 2, 2025
Euregen Biopharma Co. Ltd. has synthesized S-adenosylmethionine synthase isoform type-2 (Mat2A) inhibitors reported to be useful for the treatment of cancer.
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Cancer

SY-9453 shows efficacy at treating tumors with MTAP deficiency

May 27, 2025
No Comments
About 15% of all cancers have co-deletion of both the MTAP and CDKN2A genes, which results in sensitization to MAT2A inhibitors, thus opening a therapeutic window in these cancer types. MAT2A inhibitors have demonstrated efficacy in MTAD-deficient cancers. Shouyao Holdings (Beijing) Co. Ltd. has developed and released data for their MAT2A inhibitor SY-9453 for the treatment of MTAP-deficient cancers.
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Cancer

SY-9453 shows efficacy at treating tumors with MTAP deficiency

May 23, 2025
No Comments
About 15% of all cancers have co-deletion of both the MTAP and CDKN2A genes, which results in sensitization to MAT2A inhibitors, thus opening a therapeutic window in these cancer types. MAT2A inhibitors have demonstrated efficacy in MTAD-deficient cancers. Shouyao Holdings (Beijing) Co. Ltd. has developed and released data for their MAT2A inhibitor SY-9453 for the treatment of MTAP-deficient cancers.
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Cancer

SK Biopharmaceuticals patents new Mat2A inhibitors

March 5, 2025
SK Biopharmaceuticals Co. Ltd. has disclosed S-adenosylmethionine synthase isoform type-2 (Mat2A) inhibitors reported to be useful for the treatment of cancer.
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Biotech deal illustration

Beigene, CSPC strike $1.5B deal for phase I MAT2A inhibitor

Dec. 17, 2024
By Tamra Sami
Beigene Ltd. struck a global licensing deal with CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co. Ltd. worth up to $1.5 billion for its phase I selective methionine adenosyltransferase 2A (MAT2A) inhibitor, SYH-2039, which is being explored for solid tumors.
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Biotech deal illustration

Beigene, CSPC strike $1.5B deal for phase I MAT2A inhibitor

Dec. 13, 2024
By Tamra Sami
Beigene Ltd. struck a global licensing deal with CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co. Ltd. worth up to $1.5 billion for its phase I selective methionine adenosyltransferase 2A (MAT2A) inhibitor, SYH-2039, which is being explored for solid tumors.
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Lab glassware and scientist
Cancer

HM-100760 targets MTAP-deleted cancers via synthetic lethality

Oct. 31, 2024
Methionine adenosyltransferase 2A (MAT2A), the rate-limiting enzyme in the methionine cycle, catalyzes the formation of S-adenosylmethionine (SAM) from methionine and adenosine triphosphate (ATP).
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Cancer

Mat2A inhibitors reported in Gan & Lee Pharmaceuticals patent

Sep. 26, 2024
Gan & Lee Pharmaceuticals Co. Ltd. has described new S-adenosylmethionine synthase isoform type-2 (Mat2A) inhibitors reported to be useful for the treatment of cancer.
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3D Rendering of tumor microenvironment
Cancer

CSPC Pharmaceutical’s MAT2A inhibitor cleared to enter clinic in China

March 19, 2024
CSPC Pharmaceutical Group Ltd. has received clearance from China’s National Medical Products Administration (NMPA) to conduct clinical trials in China with SYH-2039, a highly selective methionine adenosyltransferase 2A (MAT2A) inhibitor, for advanced malignant tumors.
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Cancer

Shouyao Holdings prepares and tests new Mat2A inhibitors for cancer

Oct. 30, 2023
S-Adenosylmethionine synthase isoform type-2 (Mat2A) inhibitors have been described in a Shouyao Holdings (Beijing) Co. Ltd. patent to be useful for the treatment of cancer.
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More Articles Tagged with 'Mat2A inhibitors'

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