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Home » Keywords » myeloid-derived suppressor cells

Items Tagged with 'myeloid-derived suppressor cells'

ARTICLES

Blue cancer cell
Cancer

Research uncovers how USP15 facilitates immune evasion in colorectal cancer

July 22, 2025
No Comments
Colorectal cancer remains a prevalent and deadly form of cancer. A significant challenge to treating colorectal tumors is the creation of a suppressive tumor immune microenvironment that leads to tumor progression and resistance to immunotherapy.
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Cancer cells
Newco news

Highfield gains FDA clearance for phase I trial of liposome-based HER2 low-targeting cancer drug

June 20, 2023
By Marian (YoonJee) Chu
The U.S. FDA greenlighted Highfield Biopharmaceuticals Co. Ltd.’s IND, paving way for the Chinese immunotherapy firm to begin clinical testing its immunoliposome cancer therapy.
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Cancer cells
Newco news

Highfield gains FDA clearance for phase I trial of liposome-based HER2 low-targeting cancer drug

June 16, 2023
By Marian (YoonJee) Chu
The U.S. FDA greenlighted Highfield Biopharmaceuticals Co. Ltd.’s IND, paving way for the Chinese immunotherapy firm to begin clinical testing its immunoliposome cancer therapy.
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Colorectal cancer illustration
Cancer

CLEC7A blockade protects against colorectal tumorigenesis in mice

April 12, 2023
C-type lectin receptor is a family of molecules consisting of several proteins that recognize a broad spectrum of ligands, such as immunoreceptor tyrosine-based activation motif (ITAM) and immunoreceptor tyrosine-based inhibitory motif (ITIM), and are known to regulate diverse immunological functions.
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Multiple sclerosis-damaged myelin
Neurology/Psychiatric

miR-223 as a therapeutic target for enhancing MDSC suppressive activities

Nov. 10, 2022
Researchers from Washington University presented data from a study that aimed to identify myeloid-derived suppressor cell (MDSC) markers in patients with multiple sclerosis (MS).
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Cancer cell and DNA

Study casts further light on cancer immunotherapy

July 9, 2021
By John Fox
Translationally controlled tumor protein (TCTP) is an immunomodulator that initiates development of an inflammatory milieu in the tumor microenvironment, where TCTP regulates high myeloid-derived suppressor cell activity, researchers have reported.
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