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BioWorld - Saturday, July 19, 2025
Home » Keywords » Vyne Therapeutics Inc.

Items Tagged with 'Vyne Therapeutics Inc.'

ARTICLES

Musculoskeletal

Vyne’s BD2-selective BET inhibitor cleared by FDA for phase I

May 7, 2024
Vyne Therapeutics Inc. has received IND clearance from the FDA allowing it to initiate a first-in-human phase Ia study of VYN-202, an oral small-molecule BD2-selective BET inhibitor for autoimmune diseases.
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Dermatologic

Selective BET inhibitor VYN-202 shows promise in models of psoriasis and RA

Oct. 30, 2023
Vyne Therapeutics Inc. has released promising new preclinical data on its oral small-molecule BD2-selective BET inhibitor, VYN-202, in preclinical models of psoriasis and rheumatoid arthritis. In a well-established model, a psoriasis phenotype was induced in BALB-C mice, and treatment was administered intraperitoneally with either VYN-202, the allosteric TYK2 inhibitor Sotykto (deucravacitinib, Bristol Myers Squibb Co.) or placebo.
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Lab glassware and scientist
Inflammatory

Vyne selects development candidate from BD2-selective BET inhibitor program for immuno-inflammatory conditions

May 2, 2023
Vyne Therapeutics Inc. has selected a development candidate, VYN-202, for its oral BD2-selective bromodomain and extra-terminal (BET) inhibitor program for the treatment of immuno-inflammatory conditions.
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Lungs
Respiratory

Vyne’s pan-BET inhibitor VYN-201 shows promise in mouse model of IPF

April 20, 2023
Vyne Therapeutics Inc. has released new...
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