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Home » Keywords » Obseva SA

Items Tagged with 'Obseva SA'

ARTICLES

Pregnancy

Obseva could bring in up to $500M in Organon deal for preterm labor drug

July 27, 2021
By Lee Landenberger
Organon & Co. will license exclusive global development, manufacturing and commercial rights to ebopiprant (OBE-022) from Obseva SA. Ebopiprant is a prostaglandin F2α receptor antagonist being developed for treating preterm labor by reducing inflammation and uterine contractions. Obseva could receive tiered double-digit royalties on commercial sales and as much as $500 million in up-front and milestone payments, including $25 million to be paid at signing, up to $90 million in development and regulatory milestones and up to $385 million in sales-based milestones.
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Fallopian tubes, ovaries and uterus

Three-dimensional push with relugolix making Myovant’s appeal real

Sep. 4, 2020
By Randy Osborne
With the PDUFA date for relugolix against prostate cancer growing nearer and data in castration resistance-free patients closer still, Myovant Sciences GmbH aims to wring more from the oral, once-daily gonadotropin-releasing hormone receptor antagonist, studying it in uterine fibroids and endometriosis.
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No holiday in UF walk down Primrose lane; Obseva shares melty on Yselty

July 6, 2020
By Randy Osborne
Geneva-based Obseva SA’s top-line data from the pivotal phase III studies called Primrose 1 and 2 with GnRH antagonist Yselty (linzagolix) pleased the company, but Wall Street not so much.
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Fallopian tubes, ovaries and uterus

Calcium deposit: Obseva banks on UF data with GnRH therapy linzagolix

March 18, 2020
By Randy Osborne
Geneva-based Obseva SA’s phase III Primrose 2 trial with gonadotropin-releasing hormone (GnRH) antagonist linzagolix in heavy menstrual bleeding (HMB) due to uterine fibroids (UFs) hit the primary endpoint in 94% of patients, and the company in the second quarter of 2020 will report six-month data from the Primrose 1 study, which is also a phase III experiment, in the same indication.
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In virtro fertilization

Obseva stock plunges on phase III miss, termination of in vitro fertilization program

Nov. 8, 2019
By Cormac Sheridan
DUBLIN – Obseva SA's stock plunged 65% Thursday on news that it was terminating development of its in vitro fertilization (IVF) drug, nolasiban, after it missed the primary endpoint of a confirmatory phase III trial. The result blindsided both Obseva and investors, as the outcome was at odds with that of a previous phase III study, Implant 2, which had demonstrated a statistically significant and clinically relevant improvement in the rate of successful pregnancy at 12 weeks.
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