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Sun, May 11, 2025

IDWeek

Home » Topics » Conferences » IDWeek
  • Oct. 23, 2024

    Antifungal activity, reduced cytotoxicity with COT-832 in vitro and in vivo

    Studies evaluating the in vitro and in vivo antifungal activity, hemolytic activity and cytotoxicity of COT-832, a novel polyene macrolide antifungal that is a chemical modification of amphotericin B (AmB), were presented at IDWeek by Shionogi & Co. Ltd.
  • Influenza virus 3d illustration
    Oct. 22, 2024

    Drug-Fc conjugate protects from seasonal and pandemic influenza strains

    The influenza virus undergoes rapid and frequent antigen shifts that usually force seasonal vaccine updating. The mismatch between vaccine strains and circulating viruses leads to limited vaccine effectiveness, mainly in immunocompromised and older individuals.
  • Neprology healthy kidneys
    Oct. 22, 2024

    First-in-class antisense RNA therapy for BK virus presented

    Patients receiving a kidney transplant and who are positive for BK virus (BKV) are at risk of losing their transplant due to BKV reactivation. At this time, there are no antiviral options available for the prevention of BKV-associated nephropathy. Researchers from Aicuris Anti-infective Cures GmbH presented preclinical data on AIC-468, an antisense RNA therapy that inhibits the splicing process of a viral mRNA encoding a protein critical for BKV replication.
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